24 citations
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November 2008 in “Arquivos Brasileiros de Endocrinologia & Metabologia” Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.
24 citations
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November 1978 in “Biochemistry” α-type filaments in guinea pig hair follicles have unique structural features.
23 citations
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January 2014 in “International Journal of Biological Sciences” African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.
23 citations
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July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
22 citations
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December 2016 in “PloS one” A specific protein in chicken embryos links early skin layers to feather development.
22 citations
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August 2011 in “Journal of Supercritical Fluids” Rice bran extract might help prevent hair loss.
21 citations
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February 2017 in “PLoS ONE” RhoA helps skin stem cells grow, aiding wound healing.
21 citations
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April 1982 in “Genetics Research” Mice with the naked gene have missing or abnormal hair cells.
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September 2021 in “Nature communications” Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
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August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
20 citations
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July 1988 in “Clinics in dermatology” Thioglycolate lotions are the most popular method for permanent waving and hair straightening.
19 citations
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November 2018 in “Nutrients” Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.
19 citations
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February 2017 in “Journal of radiation research” High-dose radiation speeds up aging in skin stem cells.
19 citations
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April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
19 citations
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September 2011 in “Journal of Dermatological Science” TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.
19 citations
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August 2010 in “Journal der Deutschen Dermatologischen Gesellschaft” Certain plant extracts can effectively treat skin conditions like athlete's foot, chronic vein problems, sun damage, skin growths, vitiligo, and hair loss, and may also improve skin appearance.
19 citations
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January 2009 in “International review of cell and molecular biology” Hair's strength and flexibility come from its protein structure and molecular interactions.
18 citations
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February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
18 citations
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August 2021 in “PLoS ONE” Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.
18 citations
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July 2016 in “Medicine” Wnt/β-catenin and TGF-β pathways affect hair loss, and activating Wnt/β-catenin could be a potential treatment.
18 citations
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March 2015 in “Journal of Endocrinological Investigation” The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.
17 citations
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January 2019 in “Journal of cancer” The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
17 citations
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December 2018 in “The World Journal of Men s Health” Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
17 citations
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October 2017 in “Scientific reports” Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
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February 2015 in “Phytochemistry Reviews” Southeast Asian herbs show promise for skin and hair care, but more research is needed to confirm their effectiveness in cosmetics.
17 citations
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August 2012 in “Archives of Pharmacal Research” Acankoreoside J from Acanthopanax koreanum may help promote hair growth.
17 citations
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June 2012 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” Hair in mammals likely evolved from glandular structures, not scales.
16 citations
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April 2012 in “Journal of mammalogy” Young female Australian fur seals are losing hair due to low tyrosine and zinc levels and high pollution exposure.
15 citations
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March 2012 in “International journal of nanomedicine” Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.
15 citations
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January 1987 in “Electrophoresis” Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.