research Oral Nitroglycerin and Hair Transplant Surgery
Nitroglycerin can stop scalp necrosis during hair transplant surgery.
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research Adrenolytic and Vasodilator Therapy
New drugs like clonidine and prazosin show promise for treating high blood pressure despite some side effects.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Platelet-Released Growth Factors Modulate the Secretion of Cytokines in Synoviocytes under Inflammatory Joint Disease
Platelet-released growth factors can reduce inflammation in joint disease.
research A perspective on small molecules targeting the renin–angiotensin–aldosterone system and their utility in cardiovascular diseases: exploring the structural insights for rational drug discovery and development
Targeting the RAAS with small molecules can improve cardiovascular disease treatments.
research A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-α-Reductase in the Treatment of Androgenetic Alopecia
Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.
research Abstracts from the ASA 40thAnnual Meeting
HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
research Recent Progress in Health Benefits of Hederagenin and Its Glycosides
Hederagenin shows promise for cancer and inflammation treatment but needs modifications to improve effectiveness.
research Anti-androgenic curcumin analogues as steroid 5-alpha reductase inhibitors
Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.
research SRD5A2 and emerging therapies in androgen-driven disorders
research Can we teach old drugs new tricks?—Repurposing of neuropharmacological drugs for inflammatory skin diseases
Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
research Table 3_Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques.xlsx
Jamogenin and other molecules may help treat hair loss by inhibiting 5-alpha reductase.
research Table 4_Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques.xlsx
Jamogenin and other compounds may help treat hair loss by inhibiting 5-alpha reductase.
research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABAAReceptors
Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors
Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.
research Efficacy and safety evaluations of topical proretinal nanoparticles
Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.
research Neuroactive steroids inhibit spinal reflex potentiation by selectively enhancing specific spinal GABAA receptor subtypes
Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
research Canagliflozin alleviates progestin resistance by suppressing RARβ/CRABP2 signaling in THRB knockout endometrial cancer cells
Canagliflozin helps overcome progestin resistance in certain endometrial cancer cells.
research Table 2_Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques.xlsx
Jamogenin and other molecules from plants may help treat hair loss.
research Ovarian sex steroid receptors and sex hormones in androgenized rats
High doses of nandrolone decanoate disrupt ovarian hormones and receptors in rats, with recovery only at lower doses and longer recovery times.
research Targeted radionuclide therapy for head and neck squamous cell carcinoma: a review
Targeted radionuclide therapy shows promise for improving head and neck cancer treatment but needs more research.
research Disease modifying osteoarthritis drug discovery using a temporal phenotypic reporter in 3D aggregates of primary human chondrocytes
Aromoline and DRD4 are potential targets for osteoarthritis treatment.
research Kaempferol Rhamnosides from Geranium sibiricum as Aldose Reductase Inhibitors and Their Content by HPLC Analysis
Geranium sibiricum may help manage diabetic complications by inhibiting a key enzyme.
research Emerging and traditional 5-α reductase inhibitors and androgen receptor antagonists for male androgenetic alopecia
New treatments for male hair loss are being explored to improve effectiveness and reduce side effects.
research Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model
Ginsenoside Rb1 may help remodel hypertrophic scars effectively at a dose of 0.56 mg.
research Amphiregulin in Fibrotic Diseases and Cancer
Targeting amphiregulin may improve treatment for fibrotic diseases and cancer.
research Screening Potential Drugs From Nitric Oxide Donors for Treating Alopecia Based on Network Pharmacology and Experimental Validation
Hesperidin may help reduce hair loss by protecting hair follicles.
research Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries
Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.
research Neuroactive Steroids: Functions, Mechanisms of Action and Physiologic Relevance
Allopregnanolone may enhance alcohol's effects on dopamine neurons, influencing addiction risk.
research Novel immune mechanisms in androgenetic alopecia
Blocking GPR91 can help prevent and reverse hair loss in androgenetic alopecia.