October 2025 in “Journal of the Endocrine Society” Goserelin injections can effectively manage hyperandrogenism symptoms in postmenopausal women who can't have surgery.
January 2017 in “Springer eBooks” Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
June 2003 in “Obstetrical & Gynecological Survey” Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
July 2023 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH agonist effectively diagnoses and treats postmenopausal hyperandrogenism from ovarian sources.
1 citations
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July 2024 in “Journal of Assisted Reproduction and Genetics” October 2025 in “Journal of Obstetric and Gynaecological Practices POGS”
4 citations
,
November 2018 in “Endocrinology, Diabetes & Metabolism Case Reports” GnRH analogue can help diagnose ovarian causes of high testosterone in postmenopausal women when scans don't show the cause.
238 citations
,
February 2007 in “Journal of Neuroscience” Ovarian and stress hormones can change GABA A receptors through neurosteroids.
January 2014 in “theses.fr (ABES)” Androgens regulate Sertoli cells and affect fertility through specific receptors and coregulators.
A stable sheep ovarian cell line was created for studying reproduction and hormones.
April 2020 in “Journal of the Endocrine Society” A rare ovarian tumor caused high male hormone levels, but surgery fixed it.
43 citations
,
January 2006 in “PubMed” Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.
354 citations
,
August 1991 in “Molecular Endocrinology” Human adrenals and gonads have a unique enzyme for steroid hormone production.
9 citations
,
August 1952 in “The Journal of Clinical Endocrinology & Metabolism” A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
9 citations
,
November 2013 in “Gynecological Endocrinology” A woman had high testosterone due to an ovarian issue, which was fixed with surgery.
January 2025 in “EXPERIMENTAL ANIMALS” Gamma-ray exposure improves genome editing efficiency in mice using the i-GONAD method.
April 2019 in “Journal of the Endocrine Society” The study found that imaging might miss small ovarian tumors causing high testosterone, and suggested using certain testosterone levels and treatment responses to identify these tumors.
3 citations
,
December 2014 in “Elsevier eBooks” Male hormones and their interactions are crucial for male sexual development and characteristics.
3 citations
,
July 2019 in “Case Reports in Obstetrics and Gynecology” A young woman's rare ovarian tumor was successfully removed, improving her hormonal symptoms.
22 citations
,
February 2014 in “Arquivos Brasileiros De Endocrinologia E Metabologia” An 81-year-old woman's severe male hormone symptoms were caused by an ovarian tumor, which was treated with surgery.
2 citations
,
May 2018 in “Diagnosis” A 68-year-old woman developed male traits due to a tumor in her ovary, which was removed, returning her hormone levels to normal.
3 citations
,
January 2017 in “Gynecological endocrinology” A postmenopausal woman's excess male hormone symptoms were caused by a rare adrenal gland tissue in her ovary.
1 citations
,
April 2011 in “The FASEB Journal” Progesterone-derived neurosteroids affect GABA-A receptor expression, influencing epilepsy during menstrual cycles.
January 2024 in “Theranostics” HDAC6 helps keep ovarian follicles dormant, extending female fertility.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” Thorough evaluation is crucial for postmenopausal women with virilization to detect rare ovarian tumors.
52 citations
,
January 2016 in “Sexual Development” Both genetic and hormonal factors are crucial for bird sex differentiation, and disturbances can cause sex reversal.
November 2012 in “Experimental and Clinical Endocrinology & Diabetes” A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.
3 citations
,
April 2024 in “Molecular Human Reproduction” Paxillin may help manage androgen-related disorders like PCOS by stabilizing androgen receptor proteins.
1 citations
,
July 2015 in “AACE clinical case reports” Removing both ovaries treated the woman's excess male hormone symptoms.