research Inhibition of 5α-reductase alters pregnane metabolism in the late pregnant mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
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research Can serum vaspin levels predict clomiphene resistance in infertile women with PCOS?
Lower vaspin levels in the blood may indicate a better response to fertility treatment in women with PCOS.
research The Use of High-Density SNP Array to Map Homozygosity in Consanguineous Families to Efficiently Identify Candidate Genes: Application to Woodhouse-Sakati Syndrome
Using SNP array testing helped quickly find the gene causing Woodhouse-Sakati syndrome in two related individuals.
research The five-year effects of testosterone replacement therapy on lipid profile and glucose tolerance among hypogonadal men in Japan: a case control study
Testosterone replacement therapy improved blood sugar and fat levels without raising prostate cancer risk in Japanese men with low testosterone.
research Effect of metformin on clinical and biochemical hyperandrogenism in adolescent girls with type 1 diabetes
Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.
research Baldness and testicular cancer: the EPSAM case-control study
Bald men may have a lower risk of testicular cancer.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research Testosterone concentrations and oligomenorrhea in women with acne
Women with acne and irregular periods had higher active testosterone levels, which could suggest the usefulness of antiandrogen treatment.
research Woodhouse-Sakati syndrome (WSS)
The document reports three sisters with Woodhouse-Sakati syndrome showing typical symptoms and unusual gynecological anomalies.
research Medical consequences of long-term anabolic-androgenic Steroids (AASs) abuses in athletes
Long-term steroid abuse in athletes causes serious health risks, outweighing any benefits.
research Polycystic ovary syndrome: Challenges in adolescence
Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.
research The biology and clinical application of systemic glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Restoring neuropetide Y levels in the hypothalamus ameliorates premature aging phenotype in mice
Increasing neuropeptide Y in the brain can slow aging signs in mice.
research Origanum vulgareL. leaves extract alleviates testis and sperm damages induced by finasteride: Biochemical, Immunohistological and apoptosis genes based evidences
Oregano extract helps fix testis and sperm damage caused by finasteride.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Can the Second to Fourth Digit Ratio (2D : 4D) Be a Marker to Determine Ankylosing Spondylitis Disease Activity?
The index to ring finger ratio may indicate disease severity in female ankylosing spondylitis patients, but not in males.
research Acne in children
Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.
research Evaluation of dermatologic adverse events associated with aromatase inhibitors: insights from the FAERS database
Aromatase inhibitors can cause skin issues, especially with anastrozole and exemestane, so monitoring is important.
research Diffuse hair loss associated with hyperprolactinaemia: report of three cases
High levels of prolactin in the blood can be linked to widespread hair loss.
research Disorders of ovulation
Ovulation disorders are a major cause of infertility and menstrual problems in women.
research EFFICACY AND SAFETY OF STANDARDIZED CINNAMON BARK EXTRACT FOR THE PREVENTION OF CHEMOTHERAPY-INDUCED WEIGHT LOSS AND ALOPECIA IN PATIENTS WITH BREAST CANCER: A RANDOMIZED, DOUBLE-BLIND, AND PLACEBO-CONTROLLED STUDY
Cinnamon bark extract may help prevent weight loss and hair loss in breast cancer patients during chemotherapy and is safe to use.
research Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations
Clinicians should use social and prescription data to track trends in performance-enhancing drug use.
research Sexual dysfunction, including hypoactive sexual desire disorder: Diagnosis and treatment recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research Acupuncture in Polycystic Ovary Syndrome: Potential and Challenge
Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.
research APPLICATIONS AND SAFETY OF TESTOSTERONE CREAMS: A SYSTEMATIC REVIEW OF TOPICAL FORMULATIONS, CLINICAL EFFICACY, AND POTENTIAL RISKS
Testosterone creams and gels can be effective but have serious risks and should be used only with medical supervision.
research sc-eQTL unveil immunogenetic architecture of polycystic ovary syndrome
PCOS involves immune and genetic factors, with key roles for T cells and specific genes.
research A systematic appraisal of emerging alternative therapies in men’s health and wellness
Alternative therapies for men's health lack strong scientific support and need more research.
research Androgen receptor gene polymorphism and biological age markers in men
AR gene variations don't affect aging markers in men.
research Dehydrogenase, Cortisol, Dopamine, Zinc, and Vitamin D3 in Iraqi Patients with Polycystic Ovary Syndrome
PCOS patients have higher LDH and lower cortisol, dopamine, zinc, and vitamin D3, which may contribute to their symptoms and obesity.
research The skin and obesity
Obesity worsens skin health and losing weight can improve skin conditions.