212 citations
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May 2010 in “American Journal of Obstetrics and Gynecology” Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.
A stable sheep ovarian cell line was created for studying reproduction and hormones.
1 citations
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April 2022 in “AACE clinical case reports” A 36-year-old person with a female appearance but male chromosomes was diagnosed with a rare enzyme deficiency affecting sexual development.
December 2020 in “Research Square (Research Square)” Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.
2 citations
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October 2015 in “Obstetrics and gynaecology cases - reviews” Removing both ovaries may better treat increased male hormone levels and related symptoms in postmenopausal women when hormone therapy doesn't work.
19 citations
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March 2004 in “The Journal of Clinical Endocrinology & Metabolism” Testosterone and letrozole treatment speeds up puberty in boys with delayed development.
May 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Using GnRHa agonists helps diagnose and treat ovarian hyperthecosis when surgery isn't possible.
October 2024 in “Journal of the Endocrine Society” Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.
August 2025 in “Geburtshilfe und Frauenheilkunde” Adolescents with PCOS need tailored diagnosis and support, including lifestyle advice and managing related health issues.
77 citations
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September 1983 in “Acta Paediatrica” Dexamethasone effectively normalizes elevated steroid levels in girls with premature adrenarche.
2 citations
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January 1988 in “Deep Blue (University of Michigan)” Early puberty in girls leads to intense moods, restlessness, and greater self-certainty.
January 2024 in “Theranostics” HDAC6 helps keep ovarian follicles dormant, extending female fertility.
July 2022 in “L Endocrinologo” A 77-year-old woman with hair loss had high testosterone and 17OH-progesterone levels, but no significant findings on imaging.
October 2024 in “Journal of the Endocrine Society” Bilateral salpingo-oophorectomy resolved hyperandrogenism in a postmenopausal woman with rare ovarian tumors.
10 citations
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May 2009 in “Cases Journal” A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.
1 citations
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May 2023 in “Fertility and sterility” Men who went through puberty later had lower sperm counts and altered hormone levels, possibly affecting fertility.
March 2016 in “The Journal of Urology” The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.
November 2022 in “Journal of the Endocrine Society” A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.
January 1977 in “Case Reports in Medicine” Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.
2 citations
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March 2018 in “BMJ Case Reports” Check hormone levels in older women to find hidden conditions like certain tumors.
March 2024 in “The journal of sexual medicine” The therapies improved ejaculation disorders and sexual function in middle-aged men.
84 citations
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September 2014 in “European journal of endocrinology” Doctors should check for serious tumor causes of high androgen levels in postmenopausal women and more research is needed on this condition.
September 2020 in “Fertility and sterility” Hyperandrogenism does not affect the quality of blastocysts in PCOS patients undergoing IVF.
280 citations
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May 2005 in “Andrology” Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.
January 2026 in “JCEM Case Reports” Benign conditions can mimic serious ones in postmenopausal hyperandrogenism, requiring careful diagnosis.
October 2024 in “Journal of the Endocrine Society” Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.
January 2026 in “JCEM Case Reports” Genetics may play a significant role in gender dysphoria.
173 citations
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May 2001 in “Human reproduction update” Oestrogens are key for bone growth during puberty in both boys and girls.
19 citations
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May 2020 in “American journal of men's health” Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.
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