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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Men have higher COVID-19 mortality rates than women due to biological and lifestyle factors.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Friesian heifers take about 18 months to adapt to Kenya's climate, with hair changes not strongly linked to weight gain.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Testosterone reduces, while finasteride enhances, morphine's pain relief.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.

Hirsutism is excessive male-pattern hair growth in women, often treated cosmetically or with hormone therapy if contraception is also desired.

Dutasteride is more effective for male pattern baldness than finasteride, and black cohosh extract BNO 1055 is as effective as conjugated estrogens in treating postmenopausal symptoms, with added benefits in reducing sweating and mental symptoms.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Genetic response to androgens is key in female pattern baldness, not SHBG levels.

Severe iron deficiency lowers fertility in female rats.

Hyperandrogenism did not affect sexual function in young women.

Male tissue has more cell death than female tissue after ischemia, and some neurosteroids only protect female cells.

A rare ovarian tumor caused early puberty signs in a 1-year-old girl, but surgery reduced hormone levels.

Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.