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Reproductive gynecologists are the main referrers for male infertility evaluations in North America.

New methods may speed up drug development for male subfertility.

An unusual growth of Leydig cells in a woman's ovaries caused her excessive hair growth, which was treated successfully with surgery.

Late onset of first period and irregular development of sexual traits in teenage girls can lead to poorer reproductive health.

Ovarian hyperthecosis can cause symptoms even with normal testosterone levels, and surgery can improve these symptoms.

A woman's high testosterone levels and related symptoms improved after ovary removal surgery.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

A woman's excessive hair growth and high testosterone were caused by a rare ovarian tumor, which was successfully treated with surgery.

Stopping the drug usually helps, but tamoxifen or surgery may be needed if symptoms persist.

A rare ovarian tumor caused high testosterone and excess hair in a woman, which was resolved after tumor removal.

The document concludes that antiandrogenic drugs like cyproterone acetate and spironolactone are effective but not permanent treatments for skin-related androgenization in women.

Leydig cells can cause testosterone-secreting adrenal tumors in women.

Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.

Pediatric endocrinologists should provide early fertility counseling and preservation options to young patients at risk of infertility.

ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.

Ovarian tumors should be considered when postmenopausal women show signs of virilization.

Clomiphene Citrate can quickly restore fertility in some men after long-term steroid abuse.

Haemochromatosis can cause infertility by affecting hormone glands.

Mosaic Klinefelter syndrome can affect male fertility and may be missed in routine tests.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

Finasteride may cause breast enlargement, low testosterone a risk factor.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Individuals with male pseudohermaphroditism often do better raised as females with early surgery.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

Early detection of ovarian steroid cell tumors is crucial to prevent lasting symptoms.

Male infertility and genitourinary birth defects are often linked to genetic issues.

A 77-year-old woman with hair loss had high testosterone and 17OH-progesterone levels, but no significant findings on imaging.