2170 citations
,
September 2017 in “The Journal of Clinical Endocrinology & Metabolism” A multidisciplinary approach is crucial for safe and effective hormone treatment in gender-dysphoric individuals, with specific guidelines for adolescents and adults.
116 citations
,
December 2013 in “The Journal of Pediatrics” Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
66 citations
,
August 1999 in “The Journal of Clinical Endocrinology & Metabolism” Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.
33 citations
,
April 2015 in “Cochrane library” Some medicines can reduce excessive hair growth in women, but more research is needed to compare treatments and consider side effects.
32 citations
,
November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
30 citations
,
February 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Some medications can reduce excessive hair growth in women, but more research is needed to find the best treatment combinations.
24 citations
,
March 1996 in “Postgraduate Medical Journal” Most women with hirsutism in the UAE have polycystic ovary syndrome (PCOS).
23 citations
,
March 1994 in “Fertility and sterility” Most patients improved with oral contraceptives, but some needed additional treatment.
21 citations
,
April 2016 in “International Journal of Oncology” GnRH treatment can reduce breast cancer cell invasion.
19 citations
,
January 1997 in “Dermatologic Clinics” Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
16 citations
,
September 1990 in “Fertility and sterility” Ketoconazole can treat ovarian hyperandrogenism but should be used cautiously with monitoring and birth control.
8 citations
,
February 2021 in “Journal of the American Heart Association” Medical castration in prostate cancer patients can increase the risk of serious heart rhythm problems, so it's important to monitor heart activity during treatment.
6 citations
,
November 2015 in “JAMA” Oral contraceptives help mild hirsutism, while flutamide and spironolactone help severe cases.
4 citations
,
September 2018 in “Journal of Drug Delivery and Therapeutics” PCOS is a common hormonal disorder in women linked to several health risks and can be managed through various treatments.
4 citations
,
June 2003 in “Fertility and Sterility” Finasteride doesn't affect ovulation in normal women.
2 citations
,
February 2021 in “Brain Research” Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.
2 citations
,
July 2012 in “Obstetrics, gynaecology and reproductive medicine” Hirsutism in women often indicates health issues like polycystic ovarian syndrome and is treated with lifestyle changes, medication, and cosmetic measures.
1 citations
,
August 2025 in “European journal of medical research” Subclinical hypothyroidism in women with PCOS affects thyroid and hormone interactions but not ovary structure.
1 citations
,
September 2024 in “Journal of Clinical & Translational Endocrinology” PCOS women have more severe metabolic issues and higher androgen levels than hyperandrogenic women without PCOS.
1 citations
,
June 2023 in “Reproduction” Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
1 citations
,
January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
1 citations
,
July 2015 in “AACE clinical case reports” Removing both ovaries treated the woman's excess male hormone symptoms.
1 citations
,
October 2009 in “Current psychiatry” Choose treatments for sex offenders based on individual needs, using hormonal and nonhormonal options to reduce sexual drive.
1 citations
,
May 2007 in “PubMed” Early diagnosis and treatment of haemochromatosis are crucial for reversing organ damage and improving fertility.
July 2024 in “Journal of Pediatric Endocrinology and Metabolism” Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.
Polycystic ovary syndrome (PCOS) affects about 10% of women, is often linked to obesity and family history, and can cause irregular periods, fertility issues, and other symptoms. It's usually managed with lifestyle changes, weight loss, and medication.
July 2019 in “Mayo Clinic proceedings” The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.
April 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” PCOS shares similar genetic traits across different diagnosis criteria and is linked to other health conditions.
September 2016 in “Gynecology Obstetrics and Reproductive Medicine” Effective treatment for skin issues in women with PCOS includes oral contraceptives, antiandrogens, and other medications and procedures.
November 2010 in “Clin-Alert” Monitoring for adverse effects in clinical treatments is crucial.