research Nitric oxide-dependent vasodilation induced by minoxidil in isolated rat aorta
Minoxidil relaxes rat blood vessels mainly through nitric oxide and potassium channels.
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810-840 / 1000+ results research Evaluation of hypoglycemic and anti-hyperglycemic potential of Tridax procumbens (Linn.)
Tridax procumbens significantly lowers blood sugar in diabetic rats.
research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
research 5 Alpha Reductase Inhibitors
Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.
research IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia
IGFBP-rP1 could be a new treatment for a common type of hair loss.
research A histological study of the effect of panax ginseng versus finasteride on induced benign prostatic hyperplasia in rats with potentiality of spontaneous recovery
Ginseng was more effective than finasteride in treating enlarged prostate in rats.
research Oxyresveratrol enhances hair regeneration in human dermal papilla cell and androgenetic alopecia mouse model
Oxyresveratrol promotes hair growth and may help treat hair loss.
research Genosomes: An introspection into transfection, future perspectives and applications
Genosomes are promising for safe and effective gene delivery in therapy.
research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABAAReceptors
Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
research 12 Treatment of hirsutism with 5α-reductase inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research Comparison of Effects on Gene Expression Activity of Low-Molecular-Weight Lychee Fruit Polyphenol (Oligonol®), Adenosine, and Minoxidil in Human Dermal Papilla Cells
Lychee fruit polyphenol (Oligonol®) may regulate genes linked to cell growth and inflammation in human scalp cells.
research Redefining hormone resistance in prostate cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Mechanisms of proton inhibition and sensitization of the cation channel TRPV3
Acid can block TRPV3 from outside the cell but boost its function from inside.
research 1371 FGF7-dependent inhibition of human hair growth byan osteopontin-derived peptide: A novel solution for hirsutism and hypertrichosis?
A new peptide, FOL-005, may help treat excessive hair growth by reducing a hair growth promoter, FGF7.
research 24. 力発揮および操作性からみた下肢運動の一側優位性(神経・感覚,一般口演,第63回日本体力医学会大会)
Men with early-onset hair loss are less responsive to bromocriptine's heart and metabolism benefits.
research Topically applied glycyrrhizic acid causes hair removal in rats
Glycyrrhizic acid from sweet licorice can effectively remove hair without skin irritation.
research Table 1_Subcutaneous injection of genetically engineered exosomes for androgenic alopecia treatment.xlsx
EX104 effectively promotes hair growth and regenerates follicles in androgenetic alopecia.
research A randomized, double-blind, placebo controlled, and half-head study to evaluate the effects of platelet-rich plasma on androgenetic alopecia
PRP injections did not significantly improve hair growth in men with androgenetic alopecia.
research Oral administration of low-dose bisphenol A promotes proliferation of ventral prostate and upregulates prostaglandin D2 synthase expression in adult rats
Low doses of BPA can increase prostate growth and change hormone levels in adult rats.
research 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH
Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.
research 702 dsRNA induces ectopic KRT9 expression via WNT/β-catenin-mediated signaling
Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
research Pharmacological Role and Clinical Applications of 5α-Reductase Inhibitors-Review Article for Pharmacists and Healthcare Professionals
5α-reductase inhibitors effectively treat enlarged prostate and hair loss but require careful use due to possible side effects.
research Effect of Puerariae Radix Ethanol Extract on the Proliferation of Human Dermal Papilla Cells
Puerariae Radix extract may help hair growth by increasing cell activity.
research Mrp4, A New Mitogen-Regulated Protein/Proliferin Gene; Unique in this Gene Family for its Expression in the Adult Mouse Tail and Ear1
A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
research Proxalutamide (GT0918) Reduces the Rate of Hospitalization in mild-to-moderate COVID-19 Female Patients: A Randomized Double-Blinded Placebo-Controlled Two-Arm Parallel Trial
Proxalutamide significantly lowered hospitalization rates in women with mild-to-moderate COVID-19.
research Evaluation of Efficacy of Platelet rich Plasma on Androgenetic Alopecia: A Multimodal Assessment Using Trichoscopy, Histopathology, and CD34 Immunohistochemical Assay
Platelet-rich plasma therapy improves hair growth and health in androgenetic alopecia better than some FDA-approved treatments.
research Innovative strategies for the discovery of new drugs against androgenetic alopecia
New drug strategies are needed for better hair loss treatments.
research Allopregnanolone-mediated protective effects of progesterone on tributyltin-induced neuronal injury in rat hippocampal slices
Progesterone protects neurons from damage by converting to allopregnanolone, which works through GABAA receptors.
research REAL WORLD STUDY ON ORAL ESTRADIOL TREATMENT IN TRANSGENDER WOMEN
GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
research ¿Novedad o prudencia? El delicado equilibrio en la actualización farmacológica
New drugs face challenges due to limited evidence, and safety updates are advised for some existing medications.