research Industry updates from the field of stem cell research and regenerative medicine in June 2019
In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.
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research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Hepatology highlights
Tenofovir is more effective than adefovir for resistant hepatitis B, Fibroscan is good for assessing liver damage, regulatory T cells may help hepatitis C persist, and other insights into liver health and disease were found.
research Th1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata
CD4 T cells need IFN-γ to cause hair loss in alopecia areata.
research Platelet-Rich Plasma: Principles and Applications in Plastic Surgery
Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.
research New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice
Topical treatments can regrow hair on bald scalps.
research Activating the healing process: three-dimensional culture of stem cells in Matrigel for tissue repair
Using Matrigel with stem cells improves tissue healing.
research Regeneration of Dermis: Scarring and Cells Involved
Different fibroblasts play key roles in skin healing and scarring.
research Coronavirus Infection and Cholesterol Metabolism
Cholesterol affects coronavirus spread and could be a target for treatment.
research Ectopic olfactory receptors in human: New therapeutic possibilities
Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.
research Extensive alopecia areata: A multicenter review of 132 patients
The study found that severe alopecia areata affects any age, treatments often give temporary results, and some factors predict worse outcomes.
research Hair and nail adverse events during treatment with target therapies for metastatic melanoma
People with certain allergic conditions or higher white blood cell counts have more severe hair loss, and treating hair and nail side effects early in melanoma therapy can improve quality of life.
research Baricitinib: From Rheumatoid Arthritis to COVID‐19
Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.
research Treatment of permanent chemotherapy-induced alopecia with low dose oral minoxidil
Low dose oral minoxidil helps regrow hair in permanent chemotherapy-induced alopecia.
research Demodex Folliculitis of the Scalp: Clinicopathological Study of an Uncommon Entity
Demodex mites rarely cause scalp infections leading to hair loss, but when they do, treatment is effective.
research The importance and use of stem cells in dermatology
Stem cells show promise for treating skin conditions and aiding healing.
research Hemorrhagic cystitis in allogeneic stem cell transplantation: a role for age and prostatic hyperplasia
Older age is the main risk factor for hemorrhagic cystitis after stem cell transplants.
research Permanent chemotherapy-induced nonscarring alopecia and premature ovarian failure
Chemotherapy caused a woman's permanent hair loss and early menopause.
research Hemorrhagic Cystitis in Allogeneic Stem Cell Transplantation: A Role for Age and Prostatic Hyperplasia
Older age and prostatic hyperplasia in males increase the risk of hemorrhagic cystitis after stem cell transplantation.
research Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells
Different types of skin stem cells can change and adapt, which is important for developing new treatments.
research Management of Alopecia Due to Cancer Therapies
The document concludes that scalp cooling and treatments like minoxidil can help manage hair loss from cancer therapy.
research Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-II
The mesenchymal stem cell secretome may effectively treat various diseases as an alternative to traditional stem cell therapies.
research Cyclosporine-Induced Gingival Hyperplasia in a Patient With Lichen Planopilaris: Misfortunes Never Come Singly!
A patient's gum problems worsened after using cyclosporine for a scalp condition, but improved with a lower dose.
research 410 Oral dysbiosis in palmoplantar pustulosis patients with arthro-osteosis
People with palmoplantar pustulosis, especially with bone issues, have different mouth bacteria compared to healthy people.
research 414 A fitst-in-human study of BLZ-100 (tozuleristide) demonstrates tolerability and fluorescence contrast in skin cancer
BLZ-100 is safe for use in skin cancer surgery and may help identify cancerous tissue.
research 411 The efficacy of 1550-nm erbium-glass fractional laser treatment and its effect on the expression of insulin-like growth factor 1 and Wnt/β-catenin in androgenetic alopecia
Finasteride helps female-pattern hair loss.
research Complications in Hair Restoration
Hair transplant complications can be avoided with proper training and understanding.
research Crafting Polymeric and Peptidic Hydrogels for Improved Wound Healing
Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.
research Preparing the hair follicle canal for hair shaft emergence
A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
research Skin Commensal Antigens: Taking the Road Less Traveled
Skin bacteria can help wound healing by activating certain immune cells.