22 citations
,
February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
14 citations
,
April 2015 in “Stem Cell Research & Therapy” Granulation tissue-derived cells can aid wound healing and serve as an alternative source of stem cells for tissue repair.
10 citations
,
March 1990 in “The Journal of Dermatology” Long-term etretinate use may cause delayed wound healing and extra tissue growth after injury.
4 citations
,
February 2011 in “Dermatology reports” Acitretin can cause excess tissue growth and hair loss.
18 citations
,
September 2020 in “International Journal of Nanomedicine” Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
4 citations
,
January 2015 in “Dermatology” The erbium:YAG laser is a better, safer, and faster method for scalp surgery than the traditional method.
3 citations
,
July 2025 in “Current Issues in Molecular Biology” Dental pulp stem cells can help heal skin and mucosal wounds effectively.
3 citations
,
June 2021 in “PLOS ONE” A topical BRAF inhibitor, vemurafenib, can speed up wound healing and promote hair growth, especially in diabetic patients.
February 2018 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” Ferroportin in macrophages is crucial for hair growth and skin healing by managing iron distribution.
263 citations
,
February 2020 in “International journal of molecular sciences” ADSCs help in wound healing and skin regeneration but need more research for full understanding.
163 citations
,
October 2001 in “EMBO journal” Overexpressing follistatin in mice delays wound healing and reduces scar size.
118 citations
,
December 2003 in “Mechanisms of Ageing and Development” Thymosin β4 helps heal wounds, grow hair, and improve blood vessel formation.
113 citations
,
December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
112 citations
,
October 2008 in “Wound Repair and Regeneration” Sonic hedgehog signaling is crucial for normal wound healing.
98 citations
,
November 2014 in “PLoS ONE” Hyaluronidase speeds up wound healing and reduces inflammation.
56 citations
,
November 2012 in “Endocrinology” Vitamin D receptor is essential for proper skin healing after injury.
52 citations
,
July 2001 in “Molecular and cellular endocrinology” Activin A helps heal skin wounds and protects the brain after injury.
49 citations
,
April 2003 in “Biomaterials” Bismuth subgallate and borneol together improve skin wound healing better than when used separately or compared to other treatments.
45 citations
,
August 2018 in “Haematologica” Macrophage iron release is crucial for hair growth and wound healing.
34 citations
,
May 2021 in “Journal of Nanobiotechnology” The 3D electrospun fibrous sponge is promising for tissue repair and healing diabetic wounds.
33 citations
,
September 2012 in “Wound Repair and Regeneration” Applying calreticulin can speed up wound healing in diabetics.
32 citations
,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
28 citations
,
December 2008 in “Laboratory investigation” Activin activation in skin cells speeds up wound healing without affecting scar quality.
26 citations
,
July 2007 in “Wound Repair and Regeneration” MRL/MpJ mice heal burns slower with more scarring and less tissue regeneration than BALB/c mice.
25 citations
,
February 2021 in “Diabetes” Dock5 is important for skin healing and could help treat diabetic wounds.
24 citations
,
January 2023 in “Frontiers in Medicine” Moist Exposed Burn Ointment speeds up healing of diabetic wounds.
23 citations
,
September 2015 in “PLOS ONE” Mesenchymal stem cells, especially injected into the skin, heal wounds faster and better than chitosan gel or other treatments.
19 citations
,
August 2019 in “Seminars in Plastic Surgery” Platelet-rich plasma is beneficial in various plastic surgery applications, but more research is needed to standardize its use.
14 citations
,
February 2020 in “Stem Cells International” Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
14 citations
,
June 2016 in “Biomaterials” MAA beads improved wound healing in male mice by activating the Shh pathway, but not in females.