62 citations
,
December 1941 in “Experimental biology and medicine” Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.
7 citations
,
December 1956 in “Science” 1 citations
,
December 1956 in “Science”
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
67 citations
,
August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
37 citations
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October 2014 in “Maturitas” Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.
17 citations
,
January 2015 in “Pharmacognosy Research” A herbal mix, especially with Jatamansi, effectively darkens gray hair.
13 citations
,
May 2022 in “Cell discovery” The study found new details about human hair growth and suggests that preventing a specific biological pathway could potentially treat hair graying.
11 citations
,
July 2008 in “International Journal of Dermatology” Greying hairs may be protected from alopecia areata.
6 citations
,
March 2020 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Most people in Turkey start getting gray hair around 33 years old, with factors like age, education, hair loss, skin type, family history, and anxiety playing a role.
3 citations
,
June 2017 in “Medical lasers” A treatment combining laser energy and injections improved hair loss and unexpectedly also reduced hair graying.
Hair can naturally regain color after greying, and this change may be linked to stress levels.
May 2026 in “Archives of Dermatological Research” Genetics likely cause premature graying hair, not vitamin levels.
January 2026 in “Stem Cell Reviews and Reports” Hair graying may help prevent cancer by protecting stem cells.
November 2024 in “Jurnal Biomedika dan Kesehatan” Premature graying in young children can affect self-esteem, and addressing underlying health issues may reverse it.
January 2024 in “GeroScience” Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
September 2022 in “F1000Research” Removing hair from mice without reproductive glands led to grey hair, possibly helping to understand greying in aging.
Hair can naturally regain color, and stress might influence greying and its reversal.
Gray hair affects hair's movement and appearance, making it less bouncy and more wavy.
October 2025 in “International Journal of Homoeopathic Sciences” Homeopathy helped restore normal hair color in a 5-year-old with premature greying.
September 2022 in “International Journal of Trichology” Trichoscopic measurements help determine the severity of female pattern hair loss.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
46 citations
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April 2014 in “PLOS ONE” Gray hair may be caused by lower antioxidant activity in hair cells.
35 citations
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January 2013 in “International Journal of Trichology” Kids with early graying hair often have low levels of calcium, ferritin, and vitamin D3.
30 citations
,
April 2013 in “Journal of Investigative Dermatology” Radiation mainly affects keratinocyte stem cells, not melanocyte stem cells, causing hair to gray.
26 citations
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October 2011 in “Biological trace element research” Low copper levels might cause premature graying of hair.
21 citations
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December 2023 in “Journal of Investigative Dermatology” Hair graying is caused by damage and cell depletion but might be temporarily reversible with drugs and hormones.
17 citations
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June 2012 in “The Anatolian journal of cardiology” Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.
16 citations
,
January 2018 in “International journal of trichology” Genetics and nutritional deficiencies are key factors in premature graying of hair.
14 citations
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October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.