96 citations
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July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
93 citations
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February 2009 in “Annals of the New York Academy of Sciences” 5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
84 citations
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January 2008 in “Cold Spring Harbor Symposia on Quantitative Biology” Skin stem cells help maintain skin health, grow hair, and heal wounds.
77 citations
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July 2012 in “Journal of Investigative Dermatology” Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
64 citations
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January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
60 citations
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July 2020 in “ACS Nano” Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
56 citations
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December 2011 in “The Plant Journal” AGD1 is important for root hair development in Arabidopsis, working with phosphoinositide signaling and the actin cytoskeleton.
51 citations
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February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
50 citations
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September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
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February 2008 in “Stem Cells” Wnt10b helps blood stem cells grow after injury.
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February 2015 in “European Journal of Clinical Investigation” The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.
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July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
47 citations
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April 2000 in “The American journal of pathology” Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.
45 citations
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April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
41 citations
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September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
39 citations
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July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
37 citations
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June 2011 in “Journal of Cellular Biochemistry” Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
27 citations
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July 2018 in “Experimental dermatology” Autophagy is crucial for normal sebaceous gland function and sebum composition.
23 citations
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January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
22 citations
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October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
22 citations
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October 2012 in “Cell Transplantation” Cells treated with Wnt-10b can grow hair after being transplanted into mice.
20 citations
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May 2013 in “International Journal of Molecular Medicine” Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.
18 citations
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February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
13 citations
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February 2020 in “Cold Spring Harbor Perspectives in Biology” New methods have helped find cells that create other cells in the body.
11 citations
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January 2022 in “Theranostics” Wnt4 is essential for heart repair and could be a target for heart disease treatment.
11 citations
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July 2021 in “Physiologia Plantarum” SIPHL1 from tomato enhances plants' response to low phosphate levels.
10 citations
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August 2018 in “Experimental Dermatology” Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.
8 citations
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October 2023 in “Folia Histochemica et Cytobiologica” Exosomes from modified stem cells may help treat liver injury.
8 citations
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November 2020 in “Nature Communications” Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.