49 citations
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August 2003 in “Journal of The American Academy of Dermatology” Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.
48 citations
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May 2002 in “Journal of Anatomy” VEGFs increase blood vessel permeability, especially in diseases like cancer and heart disease.
47 citations
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May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
43 citations
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January 1999 in “Endocrinology” Cortisol increases a specific protein in bone cells, which may help explain its negative effects on bone.
39 citations
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December 2011 in “PLoS ONE” Radiofrequency exposure can stimulate hair growth by increasing IGF-1 in hair follicle cells.
38 citations
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January 2017 in “Mediators of Inflammation” Platelet-released growth factors can reduce inflammation in joint disease.
37 citations
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April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
35 citations
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January 2002 in “Scandinavian Journal of Urology and Nephrology” Finasteride reduces prostate bleeding by affecting blood vessel growth.
30 citations
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March 2008 in “Wound Repair and Regeneration” Estrogen affects scalp cell types differently, enhancing some wound healing processes.
27 citations
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February 2014 in “Experimental Dermatology” IGF-1 affects hair loss and could be a potential treatment.
26 citations
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June 2000 in “Journal of The American Academy of Dermatology” Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.
25 citations
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May 2020 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” Injecting platelet-derived growth factors into ovaries may improve IVF outcomes by enhancing egg quality and embryo health.
22 citations
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January 2011 in “Indian Journal of Dermatology/Indian journal of dermatology” Cow placenta extract may help hair grow by increasing a growth factor but is less effective than minoxidil.
18 citations
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March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
12 citations
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October 2017 in “Journal of Cosmetic Dermatology” Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.
11 citations
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May 2023 in “Journal of Cutaneous Medicine and Surgery” Plasma Rich in Growth Factors may help reduce hair loss in Frontal Fibrosing Alopecia.
10 citations
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September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
10 citations
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August 2018 in “Dermatologic Surgery” Laser treatment improves hair density and increases growth factors in androgenetic alopecia.
10 citations
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May 2016 in “Journal of Dermatological Science” PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
8 citations
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January 2016 in “European Journal of Plastic Surgery” PRGF treatment is safer and more effective for hair loss than topical minoxidil.
7 citations
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June 2015 in “European Journal of Plastic Surgery” PRGF treatment safely and effectively helps hair loss.
7 citations
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March 2015 in “The American Journal of the Medical Sciences” Finasteride helps reduce blood vessel growth in diabetic rat kidneys.
6 citations
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August 2022 in “International journal of molecular sciences” α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.
6 citations
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September 2018 in “International Journal of Molecular Sciences” PRP derivatives are likely safe for therapeutic use without harmful effects.
6 citations
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June 2009 in “Clinical and Experimental Dermatology” Topical tacrolimus reduces certain growth factors in hair follicles.
3 citations
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December 2019 in “Journal of Cosmetic and Laser Therapy” PRGF treatments increased hair number and thickness in people with hair loss, with more injections leading to better results.
3 citations
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November 2005 in “Dermatologic Surgery” Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.
3 citations
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June 2000 in “Journal of The American Academy of Dermatology” Men with balding at age 45 had higher IGF-1 and lower IGFBP-3 levels, suggesting these factors might influence male pattern baldness.
1 citations
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October 2021 in “QJM: An International Journal of Medicine” Double-spin PRP is more effective for treating female hair loss than single-spin PRP.
1 citations
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January 2021 in “European journal of medical and health sciences” PRP shows promise for treating hair loss, but more research is needed.