research Hair Loss Physiology and Transplantation Principles
Hair loss is caused by hormonal changes that shorten hair growth phases and shrink hair follicles.
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research 130 Expression of nidogen1 in basal cell carcinoma
Higher levels of nidogen1 and type IV collagen are found in basal cell carcinoma compared to normal skin.
research Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Telogen hair loss and androgenetic‐like alopecia in GAPO syndrome
A boy with GAPO syndrome had hair loss similar to male pattern baldness without hormone issues, possibly due to skin or blood vessel problems.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research Heparan Sulfate Regulates Hair Follicle and Sebaceous Gland Morphogenesis and Homeostasis
Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Hair Growth-Promoting Activity of Herbal Hair Gel Containing Brassica Oleracea Extracts
Cabbage extract in hair gel may promote hair growth and could help treat hair loss.
research Transcriptional signatures of secondary hair follicles during annual cashmere growth
Researchers identified key molecular changes in goat hair follicles that could improve cashmere production.
research Genes Expression Profiling for Hair Growth by Finasteride and Luteolin Administration in Murine Model
Finasteride and luteolin may help promote hair growth.
research The use of minoxidil in diseases associated with hair loss
Minoxidil, a medicine initially for high blood pressure, can stimulate hair growth and is promising for treating hair loss, but it may cause side effects like itching and dizziness.
research The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression
3D skin models better mimic human skin and melanoma progression than older methods.
research Neural Mechanisms of Hair Growth Control
Nerves and chemicals in the body can affect hair growth and loss.
research Multiple skin cancers in a patient within 1 year of allogeneic haematopoietic cell transplant for chronic lymphocytic leukaemia
A man got six skin cancers within a year after a cell transplant for leukemia but was cancer-free 32 months later; skin checks are important post-transplant.
research 033 IL-15 is an unexpected guardian of hair follicle immune privilege and promotes human hair growth ex vivo
IL-15 helps protect hair follicles from immune attacks and encourages hair growth.
research The Growth of Human Dermal Papilla Cells and Dermal Sheath Cells in Vitro
Epidermal growth factor (EGF) boosts the growth of hair follicle cells.
research Genetic lineage tracing in skin reveals predominant expression of HEY2 in dermal papilla during telogen and that HEY2 + cells contribute to the regeneration of dermal cells during wound healing
HEY2+ cells help regenerate skin during wound healing.
research Novel Vegan Exosome-like Biomimetic Vesicles for Skin and Hair Follicle Protection and Rejuvenation: Structural and Functional Characterization and Placebo-Controlled Clinical Efficacy Studies
Vegan exosome-like vesicles from microalgae improve skin and hair health, reducing wrinkles and enhancing elasticity.
research Unlocking the Power of Light on the Skin: A Comprehensive Review on Photobiomodulation
Light-based treatment, Photobiomodulation, shows promise for non-invasive skin therapy with few side effects.
research Author response: Coordinated hedgehog signaling induces new hair follicles in adult skin
Hedgehog signaling can create new hair follicles in adult skin but may increase cancer risk.
research Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.
A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.
research Faculty Opinions recommendation of Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia.
Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.
research Photothermal conditioning of platelet-rich plasma: mechanisms and emerging applications in hair regeneration
Photothermal conditioning of PRP shows promise for improving hair growth but needs more research for confirmation.
research Trichilemmoma.Cell biology of the normal human outer root sheath.
The outer root sheath in hair follicles changes during growth, with different keratinization processes in its layers.
research Safety and Efficacy of an Oral Nutraceutical Supplement Gummy and Peptide Serum in Promoting Hair Growth: Initial Results of A Randomized Placebo Controlled Trial with an Open Label Extension
The supplement gummy and serum safely improve hair growth in women with hair loss.
research 755 Repurposing of DPP4 inhibition to improve hair follicle activation and regeneration
Blocking DPP4 can help activate hair growth and improve hair regeneration.
research 131 Mutational landscape of extramammary Paget disease
The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.
research Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit
RANK-RANKL signaling is essential for hair growth and skin health.
research Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle
Applying certain inhibitors to the skin can promote hair growth without harming cells.
research Treatment for chemotherapy‐induced alopecia in mice using parathyroid hormone agonists and antagonists linked to a collagen binding domain
PTH-CBD agonists may help regrow hair after chemotherapy.