March 2026 in “Biomolecules” MicroRNAs play a key role in controlling hair growth and quality in sheep and goats.
October 2018 in “Springer eBooks” The document concludes that various hair disorders have different treatments, including medication, surgery, and addressing underlying causes.
Glycyrrhizic acid and licorice extract can significantly reduce unwanted hair growth.
46 citations
,
May 1986 in “Seminars in Reproductive Medicine” Testosterone and dihydrotestosterone affect hair growth, and new techniques like the folliculogram help study it, but fully understanding hair growth is still complex.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
25 citations
,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” Hair from balding and non-balding areas regrows similarly on mice.
February 2026 in “Journal of Nanobiotechnology” A new treatment using a special gel with miR-665 reduces inflammation and helps hair regrow in alopecia areata.
151 citations
,
August 2011 in “The EMBO Journal” The enzyme PA-PLA1α is important for proper hair follicle development.
81 citations
,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
418 citations
,
September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
1 citations
,
January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
118 citations
,
January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
55 citations
,
November 2010 in “Development” Hair follicles in mutant mice self-organize into ordered patterns within a week.
36 citations
,
January 2021 in “Scientific Reports” Key genes and pathways, including Wnt, NF-Kappa, and JAK-STAT, are crucial for starting Pashmina fiber growth in goats.
8 citations
,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
6 citations
,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
5 citations
,
April 2022 in “Frontiers in Medicine” Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.
1 citations
,
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
68 citations
,
December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
April 2024 in “Communications biology” Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
April 2019 in “Journal of Investigative Dermatology” Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.
24 citations
,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
January 2023 in “European endocrinology” People with alopecia have a higher risk of thyroid cancer.
81 citations
,
June 2014 in “Cold Spring Harbor perspectives in medicine” Skin has specialized touch receptors that can tell different sensations apart.
59 citations
,
March 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
46 citations
,
August 2006 in “Mechanisms of Development” Runx1 is crucial for proper hair structure and development.
10 citations
,
June 2005 in “Small ruminant research” Melatonin treatment may increase cashmere production in Spanish goats.
3 citations
,
March 2020 in “International Journal of Molecular Sciences” Thymosin β4 helps increase hair growth in Cashmere goats.