research WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
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research Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin
Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
research Radioprotection of Lung Tissue by Soy Isoflavones
Soy isoflavones can protect lung tissue from radiation damage.
research Shh maintains dermal papilla identity and hair morphogenesis via a Noggin–Shh regulatory loop
Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis
Laminin-511 is crucial for early hair growth and maintaining important hair development signals.
research Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin
High lactate dehydrogenase activity is not necessary for the growth of squamous cell carcinoma.
research Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation
Thymic transplantation normalized some T-cells but not others, maintaining immune function.
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research Cross-linked features of mouse pelage hair resistant to detergent extraction
Some mutant mice have hair with abnormal cross-linking, mainly in the cuticle, not affecting other hair parts.
research Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia
Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
research STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone
The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
research Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
research Developmental Toxicity of Levo-Alpha-Acetylmethadol (LAAM) in Tolerant Rats
LAAM caused developmental toxicity in tolerant rats without causing birth defects.
research Triple-Negative Sjogren’s Syndrome and Recurrent Pneumothorax: An Uncommon Presentation of Autoimmune Disease
Recurrent pneumothorax can occur in Sjogren's syndrome, even without common markers.
research Polysaccharide, Conjugate, and mRNA-based Vaccines are Immunogenic in Patients with Netherton Syndrome
Vaccines work well in Netherton syndrome patients, similar to healthy people.
research 267 Deep phenotyping of patients with xeroderma pigmentosum and trichothiodystrophy
Deep phenotyping helps distinguish between xeroderma pigmentosum and trichothiodystrophy, aiding in diagnosis and treatment.
research 780 Novel mechanism of UVB-mediated pigmentation through the axis of ATP-P2X7
Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.
research Microscopical characterization of known postmortem root bands using light and scanning electron microscopy
The research found that postmortem root bands in hair are likely caused by the breakdown of a specific part of the hair's inner structure after death.
research Site of beige (bg) and leaden (ln) pigment gene expression determined by recombinant embryonic skin grafts and aggregation mouse chimaeras employing sash (Wsh) homozygotes
Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.
research Epidermal Notch1 recruits innate lymphoid cells to orchestrate normal skin repair
Notch1 helps skin heal by attracting cells that aid repair.
research An Investigation of Hair and its Keratin Associated Proteins using Advanced Light Microscopy
Advanced microscopy shows hair damage and keratin proteins' roles, aiding future cosmetic treatments.
research OBESITY-RELATED FACTORS INVOLVED IN ENDOPLASMIC RETICULUM STRESS INDUCTION IN ADIPOCYTES
Adipose tissue changes in obesity can trigger stress in fat cells.
research An Investigation of Keratin 15 Function by Small Interfering Ribonucleic Acid Technology
Keratin 15 affects cell behavior and characteristics in skin cells.
research The in vitro plasticity of hair follicle dermal and mesenchymal stem cells
Hair follicle stem cells are similar to mesenchymal stem cells and can become neural-like cells under certain conditions.
research Homozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia
Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
research The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons
Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
research Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations
The new drug delivery system effectively targets lung cancer cells.
research Immunohistochemical Expression of Sox9 and CD34 in Androgenetic Alopecia Patients
CD34+ cells decrease in bald areas, while Sox9 stays high, suggesting hair loss in AGA is linked to stem cell issues.
research The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Serine is vital for hair follicle stem cells to balance hair growth and skin repair.