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N6-Methyladenosine Modification of circRNA-ZNF638 Contributes to the Induced Activation of SHF Stem Cells Through miR-361-5p/Wnt5a Axis in Cashmere Goats

research N6-Methyladenosine modification (m6A) of circRNA-ZNF638 contributes to the induced activation of SHF stem cells through miR-361-5p/Wnt5a axis in cashmere goats

2 citations , November 2022 in “Animal Bioscience”

A specific RNA modification in cashmere goats helps activate hair growth-related stem cells.

research Keratin expression in the human hair follicle

1 citations , January 1989 in “Springer eBooks”

research 1340 Basal keratinocytes exhibit age-related epigenetic and transcriptomic alterations resulting in an altered metabolic profile

April 2023 in “Journal of Investigative Dermatology”

Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.

research Expression and localization of Artemis serine 516 phosphorylation in human scalp skin

5 citations , August 2012 in “Experimental Dermatology”

Artemis phosphorylation at Ser516 may help regulate skin and hair structures.

research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis

10 citations , January 2004 in “Journal of Investigative Dermatology”

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

research P7 p63, K14 and p53 expression in epithelial layers of tumor-distant oral mucosa in patients with oral squamous cell carcinoma

March 2010 in “European Journal of Cancer Supplements”

research KLHL24-Mediated Hair Follicle Stem Cells Structural Disruption Causes Alopecia

4 citations , January 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.

research Regulation of Hematopoietic Cell Development and Hair Growth in Mouse Models: Expression Analysis of Tudor-SN and Polyamine-Regulated Proteins

November 2013 in “Tampere University Institutional Repository (Tampere University)”

Tudor-SN is important for immune cells, and polyamines can promote hair growth.

Loss-Of-Function Mutations of an Inhibitory Upstream ORF in the Human Hairless Transcript Cause Marie Unna Hereditary Hypotrichosis

research Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis

181 citations , January 2009 in “Nature Genetics”

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

research Molecular modeling and structural characterization of a high glycine–tyrosine hair keratin associated protein

16 citations , January 2017 in “Physical chemistry chemical physics/PCCP. Physical chemistry chemical physics”

The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.

research A novel point mutation of keratin 17 (KRT17) in a Japanese family with pachyonychia congenita type 2: an RNA-based genetic analysis using a single hair bulb

5 citations , June 2008 in “British Journal of Dermatology”

research A 4kb Fragment of the Desmocollin 3 Promoter Directs Reporter Gene Expression to Parakeratotic Epidermis and Primary Hair Follicles

1 citations , July 2006 in “Journal of Investigative Dermatology”

A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.

research Forkhead/winged-helix transcription factor whn regulates hair keratin gene expression: Molecular analysis of theNude skin phenotype

75 citations , April 2000 in “Developmental Dynamics”

Whn is essential for hair growth, and its malfunction causes hair loss.

research The Transcriptomics and Epigenomics of Hair Follicles

January 2024 in “Updates in clinical dermatology”

research p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis

166 citations , September 2011 in “The Journal of Cell Biology”

p63 controls Satb1 to help skin develop properly.

research Ornithine decarboxylase activity in relation to DNA synthesis in mouse interfollicular epidermis and hair follicles

34 citations , October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis”

research TRPS1 haploinsufficiency results in increased STAT3 and SOX9 mRNA expression in hair follicles in trichorhinophalangeal syndrome

2 citations , September 2016 in “Journal of Dermatological Science”

Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.

research Recurrent missense mutations in the hair keratin gene hHb6 in monilethrix

21 citations , March 2003 in “Clinical and Experimental Dermatology”

Mutations in the hHb6 gene cause the hair disorder monilethrix.

research Gsdma3 is required for hair follicle differentiation in mice

30 citations , October 2010 in “Biochemical and biophysical research communications”

The Gsdma3 gene is essential for normal hair development in mice.

research 1410 Single-cell RNA sequencing reveals POUF51 and HES3 as regulators of the stem cell population in psoriasis

April 2023 in “Journal of Investigative Dermatology”

POUF51 and HES3 are key in controlling stem cell numbers in psoriasis.

research Influence of TRPV3 mutation on hair growth cycle in mice

59 citations , September 2007 in “Biochemical and Biophysical Research Communications”

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

research Proteome Analysis of Human Hair Shaft

122 citations , January 2006 in “Molecular & Cellular Proteomics”

Human hair contains many proteins, with some being highly abundant and modified.

research Sequence, expression, and evolutionary conservation of a gene encoding a glycine/tyrosine-rich keratin-associated protein of hair.

76 citations , February 1993 in “Journal of Biological Chemistry”

KAP6 genes are conserved across species and active in hair follicles.

research Keratin Expression Provides Novel Insight into the Morphogenesis and Function of the Companion Layer in Hair Follicles

38 citations , December 2006 in “Journal of Investigative Dermatology”

Keratin patterns in hair follicles help understand hair growth and potential hair and nail disorders.

research Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration

60 citations , November 2013 in “Development”

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

research Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation

6 citations , March 2020 in “Scientific reports”

Hair growth genes work better with more glucose due to changes in gene-regulating markers.

research O04 HPV8 E6 leads to Lrig1+ keratinocyte stem cell expansion

July 2023 in “British journal of dermatology/British journal of dermatology, Supplement”

HPV8 E6 gene causes growth of certain skin stem cells.

research Impaired Keratinocyte Proliferative and Clonogenic Potential in Transgenic Mice Overexpressing 14-3-3σ in the Epidermis

15 citations , June 2011 in “Journal of Investigative Dermatology”

Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.

research Epigenetics of Colorectal Cancer

218 citations , September 2012 in “Gastroenterology”

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle.

26 citations , December 1990 in “Journal of Biological Chemistry”

Two specific genes are more active during hair growth in mice.

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