research Human hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase
Inhibiting glycogen metabolism can promote hair growth.
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research Topical Inhibition of the Electron Transport Chain Can Stimulate the Hair Cycle
Applying certain inhibitors to the skin can promote hair growth without harming cells.
research Lgr5 Stem Cells and Potential Treatments for Hair Loss
Targeting Lgr5+ stem cells and Wnt signaling may effectively treat hair loss.
research Translational frontiers: insight from lymphatics in skin regeneration
Lymphatic vessels are important for skin repair and could affect skin disease treatments.
research Brief Treatment Modalities of Alopecia Areata: Review Article
Topical corticosteroids are the preferred first treatment for children with Alopecia Areata.
research Adipogenic Differentiation of Canine Hair Follicle Stem Cells (cHFSCs)
Dog hair follicle stem cells can turn into fat cells.
research Fluorescence Activated Cell Sorting (FACS) of CK15 Cells in Canine Hair Follicular Tissue
Canine hair follicle cells show stem cell properties, aiding hair growth.
research Two-dimensional electrophoretic analysis of human hair keratins, especially hair matrix proteins
The method effectively analyzes human hair proteins, especially nonfilamentous ones.
research Using disease symptomatology to guide treatment in patients with central centrifugal cicatricial alopecia: introduction of C-CAT scoring tool
The C-CAT tool helps assess and improve treatment for central centrifugal cicatricial alopecia.
research Melanocyte stem cells: a melanocyte reservoir in hair follicles for hair and skin pigmentation
Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Androgenetic Alopecia: An Evidence-Based Treatment Update
Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.
research A matter of life and death: self‐renewal in stem cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research What causes hidradenitis suppurativa ?—15 years after
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk
Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.
research Design of a RADA16-based self-assembling peptide nanofiber scaffold for biomedical applications
RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.
research Macrophages Promote Wound-Induced Hair Follicle Regeneration in a CX3CR1- and TGF-β1–Dependent Manner
Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
research Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State
Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.
research Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond?
Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
research Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization
ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
research Pten loss in Lgr5+ hair follicle stem cells promotes SCC development
Loss of Pten in certain hair follicle stem cells increases skin cancer risk.
research A Monoallelic Two-Hit Mechanism in PLCD1 Explains the Genetic Pathogenesis of Hereditary Trichilemmal Cyst Formation
A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.
research Context-dependent effect of sPLA2-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer
sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.
research Human platelet lysate versus minoxidil stimulates hair growth by activating anagen promoting signaling pathways
Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
research Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair
Collagen XVII is important for skin aging and wound healing.
research Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles
AGA linked to inflammation, stress, fibrosis, and disturbed hair follicle stem cells.
research Adipose and Hair Function: An aPPARent Connection
Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.
research Impact of Preservation Solutions on the Trichogenicity of Hair Micrografts Ascertained by Dermal Papilla Gene Expression
Chilled ATPv-supplemented saline best preserves hair grafts' key genes.
research Hair Graying Regulators Beyond Hair Follicle
Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.