185 citations
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June 2011 in “Molecular and cellular endocrinology” Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.
176 citations
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August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
165 citations
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January 2008 in “Journal of biomaterials science. Polymer ed.” The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.
90 citations
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December 2008 in “Journal of Investigative Dermatology” Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
88 citations
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June 2019 in “Cell reports” Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
80 citations
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January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
65 citations
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May 2006 in “Journal of Investigative Dermatology” Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
61 citations
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January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
52 citations
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February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
47 citations
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August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
43 citations
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December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
37 citations
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February 2005 in “Journal of Investigative Dermatology” Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.
30 citations
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November 2020 in “Journal of Advanced Research” Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.
28 citations
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March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
27 citations
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November 2007 in “Genomics” Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
24 citations
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July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
19 citations
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September 2014 in “British Journal of Dermatology” Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.
8 citations
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October 2022 in “Regenerative Therapy” New regenerative treatments for hair loss show promise but need more research for confirmation.
6 citations
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July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
6 citations
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November 2022 in “Antioxidants” OR2AT4 helps reduce aging and cell damage in human skin cells.
5 citations
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February 2021 in “Gels” HYDRO DELUXE BIO hyaluronic acid hydrogel is compatible with skin cells, may reduce inflammation, promote blood vessel growth, and protect against oxidative stress, suggesting it could help revitalize hair follicles.
4 citations
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March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
4 citations
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January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
December 2025 in “The Journal of Cell Biology” Keratin 15 helps maintain skin cell growth and repair.
May 2025 in “Journal of Extracellular Vesicles” Erythrocyte extracellular vesicles help hair growth and skin health.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
October 2021 in “The Egyptian Journal of Hospital Medicine ” Combination therapies work better than single treatments for atrophic acne scars.
January 2018 in “Stem cell biology and regenerative medicine” The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
July 2025 in “Advanced Science” Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
April 2022 in “Journal of applied science and environmental management” Alligator pepper seed extract improved wound healing in rats.