September 2023 in “Pharmaceuticals” Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.
96 citations
,
October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
81 citations
,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
77 citations
,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
77 citations
,
July 2012 in “Journal of Investigative Dermatology” Wnt10b overexpression can regenerate hair follicles, possibly helping treat hair loss and alopecia.
58 citations
,
October 2001 in “Dermatologic Clinics” Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
53 citations
,
March 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
53 citations
,
November 2006 in “Journal of Endocrinology” Prolactin slows down hair growth in mice.
32 citations
,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
26 citations
,
July 2016 in “PLOS ONE” Activating β-catenin in certain skin cells speeds up hair growth in mice.
19 citations
,
April 2015 in “European Journal of Pharmacology” Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
13 citations
,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
5 citations
,
September 2012 in “Springer eBooks” Nanoparticles can be used to deliver drugs to hair follicles, potentially improving treatments for conditions like acne and alopecia, and could also be used for vaccine delivery and gene therapy.
1 citations
,
August 2023 in “Biomolecules & therapeutics” HAPLN1 can promote hair growth and may help treat hair loss.
1 citations
,
January 2013 in “Elsevier eBooks” The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.
January 2025 in “EXPERIMENTAL ANIMALS” Stingless bee propolis may help regenerate hair follicles and improve pigment function in chemotherapy-induced hair loss.
December 2022 in “International Journal of Biomedicine” Androgens may worsen COVID-19 and hair loss could indicate the disease's severity.
October 2018 in “Springer eBooks” The document concludes that various hair disorders have different treatments, including medication, surgery, and addressing underlying causes.
January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.
April 2016 in “Journal of Investigative Dermatology” Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.
13 citations
,
July 2004 in “Skinmed” Common types of non-scarring hair loss have various causes and treatments, but more effective solutions are needed.
9 citations
,
March 2019 in “Scientific reports” Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.
10 citations
,
June 2000 in “Primary Care” The document explains different hair loss types and treatments, emphasizing diagnosis through examination and tests, and specific treatments for each condition.
77 citations
,
July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
184 citations
,
November 2014 in “Developmental Cell” Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.
109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
68 citations
,
May 2018 in “PLOS Biology” Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.
35 citations
,
July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
32 citations
,
June 2015 in “PLOS ONE” Olive leaf compound oleuropein helps grow hair in mice.
30 citations
,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.