April 2018 in “Journal of Investigative Dermatology” Different types of stem cells in the skin contribute to the variety of melanoma forms.
August 2017 in “Journal of Investigative Dermatology” Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
December 2014 in “Bali Medical Journal” Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
April 2018 in “Journal of Investigative Dermatology” Hair pattern in androgenetic alopecia overlaps with scalp and bone demarcations, with distinct gene profiles affecting susceptibility.
Mesenchymal stem cell-derived exosomes significantly increase hair density and thickness in androgenic alopecia patients.
April 2016 in “Journal of Investigative Dermatology” The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
28 citations
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March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
91 citations
,
August 2014 in “Development” The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.
49 citations
,
October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
20 citations
,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
20 citations
,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
19 citations
,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
13 citations
,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
5 citations
,
April 2016 in “Proceedings of the Latvian Academy of Sciences. Section B, Natural, Exact and Applied Sciences” Researchers created small amber particles for use in bioactive and biocompatible fibers that could help with skin and hair restoration and are safe for infant clothing.
August 2019 in “Stem cells” New treatments for hair loss, fertility, and wound healing are being explored.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
17 citations
,
January 2013 in “Journal of Cosmetics, Dermatological Sciences and Applications” 3D bioprinting could improve skin repair and treat conditions like vitiligo and alopecia by precisely placing cells.
40 citations
,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
26 citations
,
January 2014 in “Cell Structure and Function” Human sweat glands contain stem cells capable of self-renewal and forming different cell types.
February 2024 in “Frontiers in physiology” Modifying certain signals in the body can help wounds heal without scars and regrow hair.
555 citations
,
July 2001 in “Genes & Development” Tcf3 and Lef1 are key in deciding skin stem cell roles.
375 citations
,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
359 citations
,
January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
245 citations
,
January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
232 citations
,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
211 citations
,
November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
211 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.