research 676 An underlying mechanism of hair loss in acrodermatitis enteropathica
Zinc deficiency causes reversible hair loss by disrupting hair growth and stem cell function.
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research Hair follicle stem cells and intrafollicular homeostasis
Hair follicle stem cells are crucial for hair growth and regeneration.
research The amazing miniorgan: Hair follicle
Understanding hair follicles can lead to new treatments for hair loss and skin tumors.
research Hair-growth promoting effect of bimatoprost
Bimatoprost effectively promotes hair growth.
research TrichoScan®: A useful method for measuring hair growth parameters and enhancing patient selection for hair restoration surgery
The TrichoScan method effectively measures hair growth and helps choose patients for hair restoration surgery.
research Hair-growth as anti-aging
Anti-aging treatments like hair transplants, minoxidil, and finasteride effectively promote hair growth.
research Hair density, hair diameter and the prevalence of female pattern hair loss
Hair loss caused by longer latent hair cycle and sudden miniaturization, not gradual follicle size reduction.
research Hair fragility (trichorrhexis nodosa) in alopecic Pomeranian dogs
Trichography is important for diagnosing hair fragility in Pomeranian dogs with hair cycle issues.
research Millet seed oil activates β–catenin signaling and promotes hair growth
Millet seed oil may help hair grow by activating certain cell growth signals.
research γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress
GABA contributes to stress-related hair loss, and ginkgolide A may help treat it.
research Ox40-Cre–mediated deletion of BRD4 reveals an unexpected phenotype of hair follicle stem cells in alopecia
Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
research Improving knowledge of hair loss disorders: Assessing the efficacy of a dermatologist-developed social media video library for patient education
Social media videos made by dermatologists significantly improved patient knowledge about hair loss.
research Thyroid Hormone Receptor Agonist Promotes Hair Growth in Mice
TDM10842, a thyroid hormone receptor activator, was found to effectively promote hair growth in mice.
research Description and characterization of a hair coat disorder in schipperkes
The hair coat disorder in Schipperkes is similar to Alopecia X and involves increased androstenedione levels and hair cycle arrest.
research Hair growth stimulation by a Natural Remedy: Animal Studies
The plant extract remedy Satura® Rosta promotes hair growth and regrowth without negative effects.
research Hair and Nail Manifestations of Systemic Disease
Early baldness in men may indicate risks for obesity, metabolic syndrome, insulin resistance, and heart disease, similar to women with PCOS. Alopecia areata is often linked with autoimmune diseases and mental health issues. Certain hair disorders are due to genetic issues, and chemotherapy can cause hair loss through specific biological pathways. Iron deficiency's link to hair loss is still disputed.
research Investigation of Transcriptional Gene Profiling in Normal Murine Hair Follicular Substructures Using Next-Generation Sequencing to Provide Potential Insights into Skin Disease
Hair follicles have a more inactive cell cycle than other skin cells, which may help develop targeted therapies for skin diseases and cancer.
research Cross-Signaling Between Hair Follicle Stem Cells And Dermal Lymphatic Vessels: A Systematic Review
This systematic review explores the interactions between hair follicle stem cells (HFSCs) and dermal lymphatic vessels, highlighting their role in hair growth and tissue regeneration. The review includes 10 studies, mostly in murine models, and reveals that HFSCs and lymphatic vessels engage in dynamic cross-signaling throughout the hair cycle. During the anagen phase, lymphatic vessels dilate and enhance fluid drainage, while HFSCs secrete Angptl7 in the telogen phase to maintain lymphatic function. Lymphatic endothelial cells (LECs) promote HFSC growth by secreting growth signals like IGF-1 and Sostdc1, which activate Wnt signaling. Enhanced lymphangiogenesis prolongs hair growth, whereas LEC depletion leads to hair follicle regression. A human study links aging and alopecia with reduced lymphatic networks. The findings suggest that targeting HFSC-lymphatic signaling could offer new therapeutic avenues for hair loss and wound healing.
research Cross-Signaling Between Hair Follicle Stem Cells And Dermal Lymphatic Vessels: A Systematic Review
This systematic review explores the interactions between hair follicle stem cells (HFSCs) and dermal lymphatic vessels, highlighting their role in hair growth and tissue regeneration. The review includes 10 studies, mostly in murine models, and reveals that HFSCs and lymphatic vessels engage in dynamic cross-signaling throughout the hair cycle. During the anagen phase, lymphatic vessels dilate and enhance fluid drainage, while HFSCs secrete Angptl7 in the telogen phase to maintain lymphatic function. Lymphatic endothelial cells (LECs) promote HFSC growth by secreting growth signals like IGF-1 and Sostdc1, which activate Wnt signaling. Enhanced lymphangiogenesis prolongs hair growth, whereas LEC depletion leads to hair follicle regression. A human study links aging and alopecia with reduced lymphatic networks. The findings suggest that targeting HFSC-lymphatic signaling could offer new therapeutic avenues for hair loss and wound healing.
research Bioorthogonal Click-Engineered Microneedle Patch Enables Adeno-Associated Virus-Mediated Dermal Acidic Fibroblast Growth Factor Expression for Hair Loss Treatment
A new microneedle patch effectively treats hair loss by delivering growth factors to the skin.
research Fully functional hair follicle organ regeneration using organ-inductive potential stem cells with an accessory mesenchymal cell population in an in vitro culture system
Scientists successfully regenerated functional hair follicles using specific stem cells and mesenchymal cells.
research 449 Long-Term Role of Hair Follicle Stem Cells in Epidermal Wound Healing
Hair follicle stem cells help maintain skin health after injury.
research Multi-omics identifies L-rhamnose as a metabolic regulator that enhances glycolysis to promote hair follicle growth
L-rhamnose may promote hair growth by boosting energy production in cells.
research Coordinating Stem Cell Behavior in the Hair Follicle
Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.
research Nanovesicles from Adipose Derived Stem Cells Delay Hair Follicle Degeneration and Stimulate Regeneration: a Novel Therapeutic Strategy for Androgenetic Alopecia
Nanovesicles from stem cells can help regrow hair and slow hair loss.
research Hair Dermal papilla maintain its hair inducing characteristics via autocrine exosomal miR-23a-3p
Hair growth is maintained by specific cell signals.
research Management of diffuse hair loss (Intithar al-Sha‘r) in the Unani System of Medicine: A Review
The Unani System of Medicine offers treatments for managing diffuse hair loss caused by stress and nutritional deficiencies.
research Hair Restoration: The Basics
Understanding hair follicle structure and techniques improves hair restoration outcomes.
research 525 Aptamer-Based Targeted Therapy for wound healing and hair growth promotion
Aptamers can improve wound healing and promote hair growth.
research Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice
Abnormal gene expression related to keratin causes hair loss in certain mice.