December 2014 in “Bali Medical Journal” Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.
September 2013 in “Molecular Biology” The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Advancements in hair biology include new treatments and tools for hair growth and alopecia.
33 citations
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April 2012 in “British Journal of Dermatology” Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
508 citations
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February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
211 citations
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November 2018 in “Nature Cell Biology” Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
205 citations
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August 2007 in “Experimental Cell Research” Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.
118 citations
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August 2010 in “Developmental Cell” MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.
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June 2002 in “The EMBO Journal” Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.
85 citations
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September 2013 in “International Journal of Molecular Sciences” Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.
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August 1999 in “Developmental biology” The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.
59 citations
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September 2008 in “Journal of Burn Care & Research” Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.
43 citations
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February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
42 citations
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October 2011 in “Seminars in Cell & Developmental Biology” Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.
35 citations
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May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
31 citations
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May 2015 in “Stem Cell Reports” Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.
28 citations
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August 2015 in “Journal of functional biomaterials” Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
28 citations
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March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
25 citations
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June 2021 in “Developmental Cell” Dying cells can help with faster healing and new hair growth by releasing a growth-promoting molecule.
21 citations
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October 2017 in “Journal of Investigative Dermatology” The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
19 citations
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September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
18 citations
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June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” A gene called Gk5 controls lipid production in the skin and affects hair growth.
13 citations
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December 2012 in “Cells” Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
6 citations
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May 2020 in “Scientific reports” Researchers identified genes and proteins that may influence wool thickness in sheep.
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August 2021 in “The Malaysian journal of medical sciences/The Malaysian Journal of Medical Science” Eating fewer calories improves the ability of stem cells to repair and renew the body in various tissues.
2 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.
2 citations
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March 2020 in “International Journal of Molecular Sciences” Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.
1 citations
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April 2016 in “CRC Press eBooks” Skin aging reflects overall body aging and can indicate internal health conditions.
June 2021 in “Research Square (Research Square)” The exact identity of skin stem cells and how skin cells differentiate is not fully known.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.