Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency

    August 2015 in “ Journal of functional biomaterials ”
    Amer Sehic, Øygunn Aass Utheim, Kristoffer Ommundsen, Tor Paaske Utheim
    Image of study
    TLDR Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.
    The document reviewed various pre-clinical studies on cell-based therapies for treating Limbal Stem Cell Deficiency (LSCD), highlighting the potential of different stem cell sources such as epidermal stem cells, hair follicle-derived stem cells, and bone marrow-derived mesenchymal stem cells. These studies, conducted on animal models, showed promising results in corneal reconstruction with varying degrees of success and minimal complications. The review emphasized the need for further research to identify the most effective cell types and methods for LSCD treatment, as well as the importance of standardized parameters in experiments to improve corneal regenerative medicine.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 87 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  41 upvotes 6 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community only microneedling and supplements

      in Progress Pictures  67 upvotes 6 months ago
      The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

      community A Theory on Why Microneedling Works

       172 upvotes 6 years ago
      Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

      community Do you keep gains if you stop microneedling?

      in Microneedling  15 upvotes 6 months ago
      Stopping microneedling may result in losing hair gains, as it enhances the effectiveness of treatments like minoxidil. Combining microneedling with minoxidil and finasteride is more effective than using microneedling alone.

    Similar Research

    5 / 1000+ results