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Did you mean Abnormal Hair Follicles?

GlossaryAbnormal Hair Follicles

hair follicles deviating from normal structure or function

Abnormal hair follicles refer to hair follicles that deviate from their typical structure or function, often leading to issues like hair thinning, hair loss, or unusual hair growth patterns. These abnormalities can be caused by genetic factors, hormonal imbalances, autoimmune conditions, or external factors such as trauma or certain medications. For professionals, understanding the underlying cause of these abnormalities is crucial for diagnosing and treating hair-related disorders effectively.

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Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update

research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update

52 citations , October 2012 in “Journal of Dermatological Science”

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables

research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables

86 citations , December 2001 in “Experimental dermatology”

Mutant mice help researchers understand hair growth and related genetic factors.

research Targeted expression of activated erbB-2 to the epidermis of transgenic mice elicits striking developmental abnormalities in the epidermis and hair follicles.

35 citations , April 1998 in “PubMed”

Activated erbB-2 in mice skin causes severe skin and hair abnormalities.

research The targeted overexpression of a Claudin mutant in the epidermis of transgenic mice elicits striking epidermal and hair follicle abnormalities

22 citations , May 2007 in “Molecular Biotechnology”

research Generalized hair follicle hamartoma associated with alopecia and myasthenia gravis: report of a second case*

64 citations , May 1981 in “Clinical and Experimental Dermatology”

A possible link exists between hair follicle abnormalities, hair loss, and muscle weakness.

research Delayed epidermal permeability barrier formation and hair follicle aberrations in Inv-Cldn6 mice

63 citations , April 2005 in “Mechanisms of development”

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

research From Hair to Cornea: Toward the Therapeutic Use of Hair Follicle-Derived Stem Cells in the Treatment of Limbal Stem Cell Deficiency

135 citations , October 2010 in “Stem Cells”

Hair follicle stem cells can help treat eye surface issues by becoming corneal cells.

Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen

research Prolactin and Its Receptor Are Expressed in Murine Hair Follicle Epithelium, Show Hair Cycle-Dependent Expression, and Induce Catagen

91 citations , May 2003 in “American Journal of Pathology”

Prolactin affects hair growth cycles and can cause early hair follicle regression.

research Hair follicle dystrophy in a litter of domestic cats resembling lanceolate hair mutant mice

3 citations , January 2021 in “Veterinary dermatology”

A litter of cats had a hair condition similar to a mouse mutation, leading to hair loss and abnormal hair and skin.

research Regenerative Potential of Adipose Tissue–Derived Exosomes in Treating Hair Shaft Abnormalities: A Case Report

January 2025 in “Case Reports in Dermatological Medicine”

Exosome therapy improved hair growth and quality in a child with hair issues.

research Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles

14 citations , February 2011 in “Experimental dermatology”

A protein called COMP is part of the connective tissue in normal human hair follicles and may be important for hair health.

Skin and Hair Abnormalities of Cantu Syndrome: A Congenital Hypertrichosis Due to a Genetic Alteration Mimicking the Pharmacological Effect of Minoxidil

research Skin and hair abnormalities of Cantu syndrome: A congenital hypertrichosis due to a genetic alteration mimicking the pharmacological effect of minoxidil

7 citations , January 2020 in “Journal of Dermatology”

Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.

research Laser Capture Microdissection Reveals Transcriptional Abnormalities in Alopecia Areata before, during, and after Active Hair Loss

16 citations , December 2015 in “Journal of Investigative Dermatology”

Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.

research Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools

135 citations , May 1994 in “Medical Entomology and Zoology”

Mouse models help study genetic skin diseases.

research Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex

2 citations , May 2023 in “Veterinary Pathology”

Understanding genetic variations in mice is crucial for studying skin, hair, or nail abnormalities.

research 1391 Immune cells may have a role in hair loss process caused by TRPV3 gain-of-function mutation

April 2018 in “Journal of Investigative Dermatology”

Immune cells might contribute to hair loss caused by a specific mutation.

research Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia

14 citations , October 2018 in “PloS one”

Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.

research 666 Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in follicular dystrophy and primary cicatricial alopecia

April 2018 in “Journal of Investigative Dermatology”

Mutations in Far2 mice cause hair loss due to sebaceous gland issues.

research Optical coherence tomography examination of hair

September 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE”

OCT can effectively examine and reveal details about human hair and scalp conditions.

research EXPLORATION OF THE MAHIYAT-E- MARAḌI (ETIOPATHOGENESIS) OF AMRĀḌ-E-SHA’R (HAIR DISORDERS) IN UNANI MEDICINE: A SYSTEMATIC LITERATURE REVIEW

January 2025 in “Open Science Framework”

Hair disorders significantly affect self-image, mental health, and quality of life.

research Multiple follicular abnormalities in a 1‐year old cat consistent with basaloid follicular hamartomas

March 2022 in “Veterinary dermatology”

A one-year-old cat had multiple benign skin tumors similar to those known in humans.

research Hair and its disorders : biology, pathology and management/ edited by Francisco M Camacho, Valerie A Randall, Vara H Price

January 2000 in “Martin Dunitz eBooks”

The book explains hair biology, disorders, and treatments.

research In vivo reflectance confocal microscopy: usefulness for diagnosing hair diseases

25 citations , December 2008 in “Journal of Dermatological Case Reports”

In vivo reflectance confocal microscopy is useful for evaluating hair shaft diseases but needs improvement for deeper hair follicle issues.

research Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway

113 citations , September 2005 in “Journal of Investigative Dermatology”

Applying a special compound can promote hair growth without harmful side effects.

research Epidermal abnormalities and increased malignancy of skin tumors in human epidermal keratin 8‐expressing transgenic mice

49 citations , August 2004 in “The FASEB Journal”

Mice with human skin protein K8 had more skin problems and cancer.