117 citations
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November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
9 citations
,
August 2007 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Sheep wool follicles absorb different amino acids at various rates and locations, which could affect wool growth based on diet and genetics.
3 citations
,
November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
148 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.
19 citations
,
August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
6 citations
,
March 2019 in “Dermatologic surgery” Chilled ATPv-supplemented saline best preserves hair grafts' key genes.
1 citations
,
March 2023 in “International Journal of Trichology” Platelet-rich plasma didn't increase hair length but may help keep hair follicles alive.
71 citations
,
June 2001 in “American Journal of Pathology” The p53 protein helps control hair follicle shrinking by promoting cell death in mice.
January 2023 in “International journal of biological sciences” COX2 and ATP synthase control the size of hedgehog spines.
253 citations
,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
131 citations
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November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
101 citations
,
January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
100 citations
,
May 2006 in “American Journal Of Pathology” Matriptase is crucial for skin barrier, hair growth, and may contribute to skin cancer.
71 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
61 citations
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July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
61 citations
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September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
49 citations
,
August 1999 in “Journal of Investigative Dermatology” Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.
42 citations
,
March 2006 in “Drug Discovery Today: Therapeutic Strategies” The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.
37 citations
,
November 2003 in “Veterinary pathology” Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.
31 citations
,
May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
26 citations
,
January 2007 in “Organogenesis” Bioengineering can potentially treat hair loss by regenerating hair follicles and cloning hair, but the process is complex and needs more research.
22 citations
,
June 2012 in “Journal of Investigative Dermatology” Adiponectin may stimulate hair growth and could be a potential treatment for promoting hair growth.
20 citations
,
December 2015 in “Journal of Pharmacopuncture” Thread-embedding therapy helped hair grow back in mice and might do the same in humans.
14 citations
,
March 2014 in “Experimental and Molecular Pathology” Sulfur mustard damages hair follicles and sebaceous glands in mice.
13 citations
,
January 2021 in “Journal of Cellular and Molecular Medicine” Thymosin β4 may boost hair growth by aiding stem cell movement and blood vessel formation.
13 citations
,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
13 citations
,
December 2005 in “Traffic” Syntaxin 9 helps in transporting and signaling of the EGF receptor in skin and stomach cells.
10 citations
,
January 2019 in “Biomarker Insights” Scalp cooling to prevent hair loss from chemotherapy works for some but not all, and studying hair damage markers could improve prevention and treatment.
10 citations
,
January 2010 in “Acta Histochemica Et Cytochemica” c-kit affects hair growth and color in alopecia areata and androgenetic alopecia.