31 citations
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August 2000 in “Journal of Investigative Dermatology” Stem cells are key for hair follicle recovery.
71 citations
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May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
32 citations
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May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
September 2020 in “Research Square (Research Square)” Researchers found that certain RNA sequences play a role in yak hair growth and these sequences are somewhat similar to those in cashmere goats.
83 citations
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January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
23 citations
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December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
13 citations
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December 2017 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
November 2024 in “Journal of Translational Internal Medicine” Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
224 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
53 citations
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February 2015 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is essential for normal hair growth and preventing hair loss.
42 citations
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February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
38 citations
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June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
33 citations
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April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
21 citations
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January 2024 in “Science Immunology” Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.
19 citations
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June 2020 in “Animals” Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.
16 citations
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December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
15 citations
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March 2021 in “Journal of Nanobiotechnology” A new method was developed to grow and maintain human hair follicle stem cells for hair reconstruction.
10 citations
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September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
6 citations
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April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
4 citations
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February 2022 in “Frontiers in molecular biosciences” Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
4 citations
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January 2017 in “Biological & pharmaceutical bulletin” Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.
3 citations
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December 2022 in “npj Regenerative Medicine” HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
1 citations
,
August 2023 in “Nature communications” Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
1 citations
,
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Polyamines are important in deciding hair follicle stem cell behavior, affecting hair growth and loss.
Understanding hair follicle signaling can improve hair disorder treatments.
September 2025 in “Science Advances” PADI4 enzyme slows down cell growth in developing hair follicles.
130 citations
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August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
92 citations
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June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
33 citations
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September 2019 in “Dermatologic Surgery” Using a special stem cell formula on the scalp once a month for six months helped people with hair loss grow more hair.