December 2024 in “Frontiers in Veterinary Science” Dorper sheep's wool shedding is linked to specific genes and pathways, which may help understand human hair growth.
August 2020 in “Research Square (Research Square)” Neural progenitor cell-derived nanovesicles help hair growth by activating a key signaling pathway.
242 citations
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February 2016 in “Science” Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.
January 2016 in “Research Explorer (The University of Manchester)” Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
165 citations
,
June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
130 citations
,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
87 citations
,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
76 citations
,
August 2018 in “International Journal of Cosmetic Science” Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
39 citations
,
August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
32 citations
,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
31 citations
,
April 2007 in “Experimental Dermatology” Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.
16 citations
,
April 2015 in “Lasers in Surgery and Medicine” Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
11 citations
,
April 2020 in “Life sciences” Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.
10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
6 citations
,
August 2019 in “PLOS ONE” Gambogic Amide helps maintain hair color and promotes hair growth.
6 citations
,
January 2016 in “Evidence-based Complementary and Alternative Medicine” Boiling and fermenting certain herbs can help hair grow by activating hair growth genes and pathways.
5 citations
,
February 2022 in “Frontiers in physiology” Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
1 citations
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August 2023 in “Biomolecules & therapeutics” HAPLN1 can promote hair growth and may help treat hair loss.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
100 citations
,
November 1996 in “Molecular Medicine Today” Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
66 citations
,
June 2010 in “Experimental Dermatology” The hair follicle is a great model for research to improve hair growth treatments.
354 citations
,
February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
300 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
149 citations
,
March 2004 in “Journal of Dermatological Science” Minoxidil boosts hair growth by increasing cell production and survival.
113 citations
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November 2017 in “Scientific Reports” Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
96 citations
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October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
61 citations
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December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.