April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Advancements in hair biology include new treatments and tools for hair growth and alopecia.
April 2023 in “Journal of Investigative Dermatology” CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
September 2021 in “CRC Press eBooks” Lichen planopilaris causes permanent hair loss and scarring due to damage to hair follicles and can be mistaken for other hair loss conditions.
65 citations
,
December 2000 in “PubMed” The biology of skin and hair is complex and not fully understood.
51 citations
,
May 1984 in “Journal of the American Academy of Dermatology” Benign follicular mucinosis involves immune cells attacking hair follicles.
1 citations
,
January 2013 Glucosylceramides are essential for healthy skin and proper wound healing.
July 2025 in “Journal of Investigative Dermatology” Scarring alopecia involves increased immune cells and specific gene changes near damaged hair follicles.
January 2025 in “Indian Journal of Dermatopathology and Diagnostic Dermatology” Nevus sebaceous is identified by unique skin changes, including thickened skin, fewer hair follicles, and many sebaceous glands.
September 2019 in “Journal of Investigative Dermatology” BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
Ablative CO2 laser resurfacing tightens skin by promoting collagen and new cell growth.
Ablative CO2 laser resurfacing tightens skin by destroying and regenerating skin layers.
TGF-β1 and 2 in hair follicles may be linked to hair loss in AGA.
September 2012 in “대한피부과학회지” Desmocollin 1 helps maintain skin structure during fetal development.
3 citations
,
December 2020 The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.
December 2009 in “Journal of Veterinary Clinics” The dog's back mass was a keratoacanthoma with inflammation, successfully removed without recurrence.
68 citations
,
December 1983 in “British Journal of Dermatology” Major histocompatibility antigens are found in specific skin cells and structures, but not in sweat glands.
2 citations
,
September 2020 in “Pakistan Journal of Zoology” Adult Red Sindhi cattle have thicker skin and more developed skin features than young cattle.
November 2018 in “Journal of Investigative Dermatology” Lichen Planopilaris causes irreversible hair loss due to immune attacks on hair stem cells, but modulating PPAR-γ might help treat it.
1398 citations
,
May 2008 in “Histochemistry and Cell Biology” Keratins are crucial for cell stability, wound healing, and cancer diagnosis.
184 citations
,
September 2006 in “PLoS Genetics” The Apc gene is crucial for normal skin and thymus development.
51 citations
,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
218 citations
,
April 2008 in “Genes & Development” Skin stem cells help repair damage and maintain healthy skin.
120 citations
,
August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
19 citations
,
February 2017 in “Journal of radiation research” High-dose radiation speeds up aging in skin stem cells.
10 citations
,
February 2012 in “Journal of Clinical Investigation” Advancements in skin and hair biology improve dermatology care and cosmetic treatments.
8 citations
,
March 2019 in “Open Biology” The document concludes that regenerating functional ectodermal organs like teeth and hair is promising for future therapies.
7 citations
,
November 2020 in “Experimental Dermatology” Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
5 citations
,
October 2020 in “Bioengineering & translational medicine” Researchers used a laser to create advanced skin models with hair-like structures.