research Advancements in 3D skin bioprinting: processes, bioinks, applications and sensor integration
3D skin bioprinting has advanced but still faces challenges like safety and the need for better integration with sensors.
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90-120 / 1000+ resultsresearch The Autoimmune Regulator (AIRE), Which Is Defective in Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Patients, Is Expressed in Human Epidermal and Follicular Keratinocytes and Associates With the Intermediate Filament Protein Cytokeratin 17
AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
research Homozygous whole body Cbs knockout in adult mice features minimal pathology during ageing despite severe homocysteinemia
Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.
research Whole exome sequencing in Alopecia Areata identifies rare variants in KRT82
Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.
research Targeting the Gut Microbiota with Pro- and Postbiotics: Emerging Strategies against Alopecia
Modifying gut bacteria with pro- and postbiotics may help treat hair loss.
research Transcriptomic Analysis Provides Molecular Insights into Skin Development in Dezhou Donkey Foals
Skin maturation in Dezhou donkey foals involves better barrier function, hair growth, and less collagen production.
research Ligand-Independent Vitamin D Receptor Actions Essential for Keratinocyte Homeostasis in the Skin
Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.
research 440 Charting the Spatially Resolved Hair Follicle Stem Cell Niche: A Multi-Omics Atlas of Healthy and Diseased Scalp
Disrupted cell interactions in hair follicles contribute to hair loss in androgenetic alopecia.
research Faculty Opinions recommendation of Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation.
A balance between BMP and Wnt signals is crucial for hair follicle stem cell function and hair growth.
research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes
Keratin 15 helps maintain tissue integrity and is reduced in activated keratinocytes.
research Alopecia areata and the gut—the link opens up for novel therapeutic interventions
Gut health may influence Alopecia Areata, suggesting new treatments.
research Promotion of homology-directed DNA repair by polyamines
Polyamines help fix DNA damage accurately in cells.
research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome
The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.
research Expression and Function of Group IIE Phospholipase A2 in Mouse Skin
sPLA2-IIE is crucial for normal hair follicle structure and skin health.
research Comparative biology of tissue repair, regeneration and aging
The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
research Eavesdropping on the conversation between immune cells and the skin epithelium
Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
research The BLMP-1 transcription factor promotes oscillatory gene expression to achieve timely molting
BLMP-1 is important for regular molting and gene expression cycles in worms.
research 320 Desmoglein 3-mediated mechanical transadhesion controls epithelial stem cell quiescence
Desmoglein 3 is important for keeping hair follicle stem cells inactive and maintaining their special properties.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Ox40-Cre–mediated deletion of BRD4 reveals an unexpected phenotype of hair follicle stem cells in alopecia
Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
research Hair follicle regeneration suppresses Ras-driven oncogenic growth
Hair follicle regeneration may slow tumor growth.
research Hair follicles modulate skin barrier function
Hair follicles play a crucial role in regulating skin barrier function.
research Spatiotemporal immunomodulation by engineered hair follicle stem cell-derived nanovesicles enables scarless regeneration of infected wounds
Engineered nanovesicles from hair follicle stem cells enable scarless healing of infected wounds.
research Cell Movement in the Hair Follicle Dermis – More Than a Two-Way Street?
DS cells in hair follicles can help form and restore hair, especially in hair loss conditions.
research Eccrine sweat glands associate with the human hair follicle within a defined compartment of dermal white adipose tissue
Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
research Hair follicle stem cells:In vitroandin vivoneural differentiation
Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
research Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice
Only skin melanocytes, not other types, can color hair in mice.
research Cutaneous neuroimmunology – lessons from the hair follicle
Stress and certain chemicals affect hair growth by interacting with the immune and nervous systems.