July 2025 in “International Journal of Biological Macromolecules” Fucoidan may help regrow hair and reduce inflammation in hair loss.
103 citations
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April 2005 in “Experimental dermatology” Prostaglandin F2alpha and related compounds can increase hair growth and darken hair in mice.
22 citations
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July 2012 in “International Journal of Trichology” Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
May 2025 in “Scientific Reports” Oxyresveratrol promotes hair growth and may help treat hair loss.
January 2023 in “Journal of cosmetic dermatology” The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
February 2026 in “Trends in Sciences” i-PRF-derived exosomes can effectively promote hair growth and improve hair health in androgenetic alopecia.
June 2008 in “Experimental Dermatology” 17-beta estradiol and prednisolone may help regrow hair damaged by chemotherapy.
1 citations
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August 2022 in “Pigment Cell & Melanoma Research” New mouse models help study melanocytic cells for melanoma research.
A skin model using hair and skin cells can mimic human skin for research.
August 1994 in “Toxicology in Vitro” A lab model of human skin was created to study skin tumor promoters without using actual human skin.
69 citations
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June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
54 citations
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March 1991 in “Proceedings of the National Academy of Sciences” This model can replace animal testing for quick, cost-effective skin toxicity tests.
April 2019 in “Journal of Investigative Dermatology” Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.
July 2023 in “Dermatology practical & conceptual” The machine learning model effectively assesses the severity of hair loss and could help dermatologists with treatment decisions.
August 2010 in “Journal of Investigative Dermatology” New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.
July 2010 in “British Journal of Dermatology” New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.
36 citations
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July 2004 in “Apmis” Fluorescent proteins in mouse models effectively visualize tumor blood vessel growth.
16 citations
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November 2017 in “British Journal of Dermatology” Cells in hair die by breaking down their DNA and mitochondria as they form keratin.
14 citations
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February 2022 in “The Journal of clinical investigation/The journal of clinical investigation” Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
6 citations
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April 2017 in “Journal of Dermatological Science” Ovariectomized mice mimic postmenopausal hair loss, and estradiol helps maintain hair density.
1 citations
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December 2024 in “The Journal of Dermatology” The study developed mouse models to help research and treat hair and sweat gland issues.
4 citations
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July 2024 in “Animals” A new depilation method using cold wax reduces injury and improves hair growth studies in mice.
2 citations
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December 2022 in “Journal of Biochemistry and Molecular Biology” Organoids created from stem cells are used to model diseases, test drugs, and develop personalized and regenerative medicine.
October 2013 in “Journal of Investigative Dermatology” Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
1 citations
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January 1997 in “Journal of Investigative Dermatology” RU58841, an androgen receptor blocker, significantly increased hair density, thickness, and length in monkeys when applied topically daily for several months.
Mouse hair follicles grow best in a special medium, especially when cut and from adult mice.
TGF-β1 and FGF-18 are key in hair loss, and Minoxidil helps hair growth.
44 citations
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November 2014 in “Tissue Engineering Part C Methods” Porcine skin varies by region, affecting its use as a human skin model.
August 2025 in “Frontiers in Pharmacology” Periplaneta americana extract helps hair regrowth by reducing inflammation and improving skin bacteria balance.
13 citations
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January 2016 in “Annals of Dermatology” Stress can slow hair growth by affecting certain cells and pathways.