research Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices
Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
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research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury
Sebaceous glands can regenerate after injury using stem cells from hair follicles.
research Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Mechanisms and cell lineages in lymphatic vascular development
Lymphatic vessels develop from various cell types and mechanisms, not just veins.
research An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration
Epidermal signaling helps regenerate fingertip tissue.
research 1405 Cellular and molecular characterization of sebaceous gland self-renewal and regeneration following complete genetic ablation
The research found that a protein called PPARg is important for the formation and healing of sebaceous glands, which can regenerate independently from hair follicles.
research Developmental Regulation of Prion Expression in Cattle and Mouse Embryonic Stem Cells
PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
research Prodrugs of butyric acid from bench to bedside: Synthetic design, mechanisms of action, and clinical applications
New butyric acid prodrugs show promise for cancer treatment, anemia management, and protecting hair from chemotherapy damage.
research Stem Cells in Dermal Wound Healing
Stem cells help heal skin wounds by supporting tissue repair and regeneration.
research Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures
Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
research The effects of sodium metasilicate on the spinal motoneuron recovery following sciatic nerve injury
Sodium metasilicate improved spinal motoneuron recovery after sciatic nerve injury in rats.
research L'idea di fenomeno fra Kant ed Husserl
Increased Wnt signaling causes hair graying by depleting melanocyte stem cells in aged mice.
research JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
JunB is crucial for maintaining healthy skin and hair follicles.
research Experimental and early investigational drugs for androgenetic alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research Directed Expression of Keratin 16 to the Progenitor Basal Cells of Transgenic Mouse Skin Delays Skin Maturation
Keratin 16 delays skin maturation and affects skin and hair development in mice.
research Stimulation of mouse hair regrowth by exosomes derived from human umbilical cord mesenchymal stem cells
Exosomes from human stem cells can help regrow hair in mice.
research Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling
Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
research The involvement of Elf5 in regulating keratinocyte proliferation and differentiation processes in skin
Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
research Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin
WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
research Identification of the cell lineage at the origin of basal cell carcinoma
Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
research 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts
Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
research Ephrins Negatively Regulate Cell Proliferation in the Epidermis and Hair Follicle
Ephrins slow down skin and hair follicle cell growth.
research Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles
Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
research Male androgenetic alopecia is due to hair follicle stem cell inactivation
Male hair loss is caused by inactive hair follicle stem cells.
research Hair follicle stem cells: A new arena
Hair follicle stem cells have significant potential for treating various disorders.
research Understanding the functional contribution of dermal stem cells to hair follicle regeneration and skin wound healing
Dermal stem cells help regenerate hair follicles and heal skin wounds.
research Immune modulation of hair follicle regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.