13 citations
,
December 1940 in “The journal of nutrition/The Journal of nutrition” Lack of certain vitamins causes fur loss and greying in silver foxes.
April 2014 in “Journal of evolution of medical and dental sciences” Women over forty can maintain skin and hair health with lifestyle and dietary changes.
March 2026 in “International Journal of Homoeopathic Sciences” Premature greying is common in children, especially ages 11-15, and homoeopathy might help.
688 citations
,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
260 citations
,
January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
175 citations
,
November 2009 in “PLOS ONE” Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.
70 citations
,
March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
66 citations
,
March 2019 in “Cellular and Molecular Life Sciences” Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.
41 citations
,
December 2018 in “Experimental Dermatology” Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
30 citations
,
April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
26 citations
,
September 2012 in “Cell Reports” B-Raf and C-Raf are essential for maintaining melanocyte stem cells to prevent hair graying.
24 citations
,
March 2018 in “Pigment Cell & Melanoma Research” The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.
9 citations
,
January 2015 in “Annals of dermatology/Annals of Dermatology” Alopecia areata in elderly people is usually mild and responds well to treatment.
7 citations
,
January 2016 in “Hair therapy & transplantation” People with early graying hair often have lower levels of iron, ferritin, and calcium.
2 citations
,
October 2009 in “The FASEB Journal” Stress does not greatly speed up aging or hair loss in politicians.
2 citations
,
July 2022 in “Indian Journal of Dermatology Venereology and Leprology” Early hair greying may increase the risk of heart disease.
1 citations
,
October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
January 2025 in “Cellular and Molecular Life Sciences” BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
December 2021 in “Dermatology research” Low levels of vitamin B12, ferritin, and calcium are linked to premature graying of hair.
June 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Stress causes hair graying by overactivating nerves that deplete color-giving stem cells.
June 2009 in “Pigment Cell & Melanoma Research” Preventing hair graying may be possible by managing oxidative stress and activating melanocyte stem cells.
July 2007 in “Cancer biology & therapy” Removing a key gene in mice leads to premature aging and loss of stem cells.
January 2004 in “Giornale di Metafisica: revista bimestrale di filosofia” Increased Wnt signaling causes hair graying by depleting melanocyte stem cells in aged mice.
January 1974 in “OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)” Oxidative stress causes hair graying by damaging hair follicle melanocytes more than skin melanocytes.
January 2020 in “Medpulse International Journal of General Medicine/Medpulse International Journal of Medicine” Premature graying of hair is often linked with other health issues, but treatment with biotin, zinc, and calcium pantothenate is not very effective.
December 2008 in “Enzyme and Microbial Technology” New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
January 2025 in “American Journal of Stem Cells” Melanocyte stem cells hold promise for skin regeneration and treating pigmentation issues.
114 citations
,
February 2012 in “International Journal of Dermatology” Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.
January 2026 in “Medicina” Premature graying of hair is common among students and linked to genetics, smoking, keto diet, and hair coloring.
January 2022 in “International journal of Ayurveda and pharma research” Premature graying of hair is linked to an imbalance of body energies in Ayurveda and treatment varies based on the specific imbalance.