April 2023 in “Journal of Investigative Dermatology” Blocking casein kinase 1 in skin cells can help melanocyte precursors move better, potentially helping with conditions like vitiligo or gray hair.
March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology” m-Aminophenol in hair dye can cause skin cell toxicity and stress responses.
rhKGF2 significantly promotes hair growth and follicle development.
Testosterone and dihydrotestosterone can slow down the growth of certain hair follicle cells.
July 2022 in “Journal of Investigative Dermatology” Skin bacteria help hair regrow by boosting cell metabolism.
105 citations
,
May 2013 in “Biomaterials” Human hair keratin hydrogel may aid nerve repair better than traditional methods.
93 citations
,
July 2006 in “Journal of Investigative Dermatology” K25, K27, and K28 are found in all inner root sheath layers of hair, while K26 is only in the cuticle.
90 citations
,
July 1993 in “Journal of Investigative Dermatology” 79 citations
,
March 2005 in “Journal of Medical Genetics” A mutation in the hHb3 gene is linked to the hair disorder monilethrix.
75 citations
,
September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
68 citations
,
February 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Keratin films from human hair can potentially replace human nail plates for drug testing.
55 citations
,
January 2013 in “International Journal of Cosmetic Science” African hair's keratin structure is influenced by its higher lipid content.
52 citations
,
May 2006 in “Journal of Structural Biology” Keratin-associated proteins help link filaments and affect keratin's strength.
42 citations
,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
41 citations
,
July 2020 in “Colloids and surfaces. B, Biointerfaces” Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.
41 citations
,
May 2012 in “Advanced Healthcare Materials” Human hair keratins improve cell adhesion and growth on culture surfaces.
40 citations
,
June 2013 in “Journal of cosmetic dermatology” Brazilian keratin treatments can straighten hair but may contain harmful formaldehyde.
38 citations
,
July 1993 in “Journal of Investigative Dermatology”
36 citations
,
July 2019 in “Journal of Materials Science Materials in Medicine” Human hair keratin helps repair nerve damage in rats.
34 citations
,
November 1998 in “Journal of Investigative Dermatology” A common mutation in the hHb6 gene is linked to monilethrix, but other factors may also play a role.
28 citations
,
December 1997 in “Journal of Biological Chemistry” A genetic mutation in the hHa1 gene creates a smaller, but still functional, hair protein without causing hair problems.
26 citations
,
May 2001 in “British Journal of Dermatology” Pilomatrixomas likely originate from the hair matrix due to changes in hair keratin expression.
23 citations
,
January 2015 in “Stem cells international” Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
20 citations
,
October 1995 in “Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression” hHb1, hHb3, and hHb6 mRNAs start expressing at the same time in hair follicles.
19 citations
,
December 2006 in “Journal of Structural Biology” Type I and Type II keratin chains can form heterodimers despite sequence differences.
18 citations
,
February 1992 in “Molecular Biology Reports” A specific type II hair keratin was identified and found in hair cortex and tongue cells.
9 citations
,
January 2021 in “BioMed research international” Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
8 citations
,
May 2020 in “International journal of biological macromolecules” Certain treatments can increase protein binding to natural hair but are less effective on permed hair.
5 citations
,
October 2002 in “PubMed” Human hair keratin scaffolds help repair injured muscles by breaking down and activating muscle cell growth.
3 citations
,
December 2021 in “Materials today communications” A new film made from human hair supports skin cell growth better than collagen.