154 citations
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October 1996 in “Proceedings of the National Academy of Sciences of the United States of America” Estrogen affects hair growth and skin cell multiplication.
108 citations
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November 2006 in “Phytomedicine” Green tea component EGCG could potentially promote human hair growth.
106 citations
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June 2005 in “Journal of Investigative Dermatology” The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.
101 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
77 citations
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January 1980 in “Carcinogenesis” TPA is about 50 times more effective at promoting tumors than MZ.
71 citations
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October 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” HFMs can help study hair growth and test potential hair growth drugs.
44 citations
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June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
41 citations
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June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
41 citations
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July 1994 in “Journal of Dermatological Science” Hair follicle cells need complex interactions to fully differentiate.
38 citations
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June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
33 citations
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January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
26 citations
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January 2019 in “Experimental Dermatology” Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.
18 citations
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November 2016 in “PeerJ” Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
15 citations
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December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
10 citations
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June 2019 in “Journal of Tissue Engineering and Regenerative Medicine” Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
10 citations
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January 2013 in “Journal of skin cancer” PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.
9 citations
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August 2017 in “Photochemistry and Photobiology” Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
8 citations
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August 2014 in “Biochemical and Biophysical Research Communications” ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.
8 citations
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May 2013 in “Journal of Investigative Dermatology” Different problems with hair stem cell renewal can lead to hair loss.
6 citations
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April 2020 in “Applied sciences” Hair growth medium helps heal wounds and regrow hair in mice.
6 citations
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June 2017 in “Asian journal of beauty & cosmetology” Rosa multiflora root extracts may help promote hair growth and have anti-aging benefits.
5 citations
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September 2020 in “Molecules” Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.
3 citations
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June 2017 in “Journal of Biomaterials Applications” Keratin extract from human hair was found to promote hair growth in mice.
1 citations
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April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
12 citations
,
May 2016 in “Experimental Dermatology” A new skin model from hair follicles is a safer, simpler alternative for skin tests.
11 citations
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October 2016 in “Biomedicine & Pharmacotherapy” Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
1 citations
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April 2016 in “Journal of Investigative Dermatology” Targeting specific T cells may help treat alopecia areata.