Hair germ cells differ from epidermal cells in keratin expression, and specific keratins form after hair differentiation.
January 1990 in “The Nishinihon Journal of Dermatology” Follicular structures help differentiate keratoacanthoma from squamous cell carcinoma.
12 citations
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October 2007 in “PubMed” Keratin helps protect and strengthen hair, reducing damage and color fading.
2 citations
,
January 2004 in “Sen i Gakkaishi” Human hair and nail proteins are unlikely to cause allergic reactions.
January 2000 in “Acta Academiae Medicine Militaris Tertiae” Different keratins in hair follicles can help identify hair tumor origins.
75 citations
,
October 1999 in “Differentiation” Mouse keratin 6 isoforms have different expression patterns in various tissues.
60 citations
,
March 2006 in “Journal of Medical Genetics” A mutation in the KRTHB5 gene causes hair and nail issues.
21 citations
,
January 1995 in “Molecular Biology Reports” Scientists discovered two versions of a new human hair keratin gene.
14 citations
,
January 2012 in “Proteins” Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
11 citations
,
January 2016 in “International Journal of Biological Macromolecules” Enzymatic phosphorylation of hair keratin improves the effectiveness of hair products with cationic ingredients.
7 citations
,
January 1990 7 citations
,
January 1959 in “Canadian Journal of Chemistry” Human and horse hair have similar end groups to wool and feathers.
6 citations
,
February 2013 in “British Journal of Dermatology” Androgens significantly regulate hair keratin K37 expression.
4 citations
,
May 1998 in “PubMed” The Bsk mutation doesn't involve keratin gene recombination and its cause is unknown.
August 2024 in “Advanced Healthcare Materials” RK81 can help promote hair growth.
January 2024 in “Archives of Biological Sciences (Beograd)” AP collagen peptides may help hair grow better and become stronger.
November 2023 in “Advanced Science” A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.
Hair keratin treatments can be harmful, potentially causing health issues like skin reactions and cancer.
114 citations
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May 2001 in “Development” Overexpression of Hoxc13 in hair cells causes hair loss and skin issues.
85 citations
,
October 2007 in “International Journal of Dermatology” Curly hair shape is due to uneven growth patterns in the hair follicle.
30 citations
,
January 1999 in “Journal of Cutaneous Pathology” Spiny keratoderma may be ectopic hair formation on palms and soles.
28 citations
,
January 2016 in “RSC Advances” A non-toxic formula using polycarboxylic acids strengthens and improves hair.
27 citations
,
January 2000 in “Developmental Dynamics” Mutations in the Whn gene affect hair keratin gene expression differently.
21 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Most mouse hair keratin genes are on chromosomes 11 and 15.
15 citations
,
January 1996 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” Keratin gene regulation was emerging, with a key transcription factor found to influence hair growth and gene expression.
12 citations
,
January 1934 in “Proceedings of the Royal Society of London Series B Containing Papers of a Biological Character” Stretched hair has a similar structure to natural silk, showing hair's elasticity involves reversible changes within its molecules.
9 citations
,
January 1981 Nucleophilic reagents break down hair keratin, forming more lanthionine and lysinoalanine than in wool.
7 citations
,
November 2007 in “Differentiation” The NF-κB effector p65/RelA activates hair keratin genes, aiding hair formation.
6 citations
,
April 2012 in “Journal of Oral Pathology and Medicine” Rushton's hyaline bodies form from hair keratin and blood substances.
3 citations
,
November 2017 in “International Journal of Cosmetic Science” Solute binding to hair keratin is mainly driven by hydrophobic interactions and changes with pH.