May 2023 in “Vestnik dermatologii i venerologii” Early-stage male pattern baldness shows two types of hair loss: one on the top of the head linked to hormonal changes, and another at the back of the head. The top hair loss responds well to specific treatment, while the back hair loss does not.
January 2013 in “Hair transplant forum international” Minoxidil and finasteride are effective for male hair loss; minoxidil also helps female hair loss, with some treatments needing more research.
October 2022 in “Hair Transplantation” Male pattern hair loss is mainly caused by genetics and hormones, especially DHT.
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January 2015 in “Hair therapy & transplantation” Some supplements and hormones can increase hair loss by raising DHT levels.
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November 2020 in “Journal of Cosmetic Dermatology” The ingredients may help prevent hair loss and aging by boosting hair growth signals and reducing stress and hormone effects.
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July 2019 in “Journal of the Korean Society of Food Science and Nutrition” Platycodon grandiflorum extract may help prevent hair loss.
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December 2018 in “Meta Gene” Certain gene variations increase male hair loss risk, influenced by hormone levels.
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July 2021 in “Journal of Dermatological Treatment” Finasteride helps hair growth but may cause sexual side effects and depression.
February 2024 in “Biomedicines” Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.
January 2009 in “Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine” Yifa compound effectively treats female pattern hair loss and lowers DHT and DHEA levels.
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June 2018 in “PubMed” Serenoa repens extract helps regrow hair and repair hair loss by activating certain cell growth pathways.
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December 2008 in “PubMed” Finasteride 1 mg helps prevent more hair loss in men with male pattern baldness.
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May 2021 in “Dermatologic Clinics” The document concludes that more research is needed to understand hair loss in men and to find new treatments.
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April 2024 in “Journal of Pharmaceutical and Pharmacological Sciences” The mouse models are effective for testing new hair loss treatments.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Finasteride and dutasteride are the most evidence-supported pharmacological treatments for androgenetic alopecia (AGA) in both men and women. Finasteride 1 mg/day reduces serum DHT by about 70%, while dutasteride 0.5 mg/day achieves approximately 90% suppression, with dutasteride showing slightly greater hair count gains. A pivotal trial found dutasteride 2.5 mg superior to finasteride 5 mg/day, but the 0.5 mg dose is standard due to its efficacy and lower systemic exposure. Genetic factors, particularly androgen receptor variations, significantly influence treatment response. In women, higher doses of finasteride and variable doses of dutasteride are effective, especially in postmenopausal and some premenopausal groups. The choice between these drugs involves balancing DHT suppression, drug half-life, and tolerability, with genetic modifiers being an important area for future research.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Finasteride and dutasteride are the most evidence-supported pharmacological treatments for androgenetic alopecia (AGA) in both men and women. Finasteride 1 mg/day reduces serum DHT by about 70%, while dutasteride 0.5 mg/day achieves approximately 90% suppression, with dutasteride showing slightly greater hair count gains. A pivotal trial found dutasteride 2.5 mg superior to finasteride 5 mg/day, but the 0.5 mg dose is standard due to its efficacy and lower systemic exposure. Genetic factors, particularly androgen receptor variations, significantly influence treatment response. In women, higher doses of finasteride and variable doses of dutasteride are effective, especially in postmenopausal and some premenopausal groups. The choice between these drugs involves balancing DHT suppression, drug half-life, and tolerability, with genetic modifiers being an important area for future research.
Finasteride can help with hair loss but may cause mental health issues like depression and anxiety.
June 2025 in “Journal of Photochemistry and Photobiology B Biology” UVA exposure worsens hair loss by activating a specific cell pathway.
May 2025 in “Journal of the American Academy of Dermatology” Bicalutamide shows promise for treating female hair loss.
November 2024 in “Journal of Cosmetic Dermatology” The plant extracts may help treat hair loss by promoting hair growth and reducing DHT levels.
June 2024 in “Korean Journal of Pharmacognosy” The compound from Rhododendron mucronulatum roots may help treat male pattern hair loss.
June 2024 in “Journal of Education, Health and Sport” Androgenetic alopecia can be treated with minoxidil and finasteride, requiring long-term use and patient cooperation.
July 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Pumpkin seeds may help treat hair loss by blocking a key enzyme.
New treatments for hair loss should target eight main causes and use specific plant compounds and peptides for better results.
November 2022 in “Journal of Investigative Dermatology” The lotion with specific plant extracts effectively increased hair growth and improved hair cycle in subjects after 3 months.
December 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Topical finasteride is promising for hair loss with minimal side effects but needs more research and approval.
Genetic differences may influence male pattern hair loss in Russians.
January 2014 in “프로그램북(구 초록집)” 5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.
March 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Dutasteride helps reduce male pattern hair loss, but may cause side effects like altered libido and erectile dysfunction.
April 2025 in “Antioxidants” Rhus semialata gall extract and Penta-O-Galloyl-β-D-Glucose may effectively reduce hair loss.