research CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties
CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
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research Aging in hair follicle stem cells and niche microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
research Hair darkening in porphyria cutanea tarda
Two patients with porphyria cutanea tarda experienced their grey hair turning dark again.
research Age-related hair changes in men: Mechanisms and management of alopecia and graying
Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.
research Hair Biology
The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
research Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata
Gonadal hormones significantly affect the severity of alopecia areata in mice.
research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis
P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.
research Hair repigmentation associated with the use of lenalidomide: Graying may not be an irreversible process!
An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.
research Hair Pigmentation: A Research Update
Hair color is determined by different melanins and changes with age.
research Anatomy and Physiology of Hair
Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
research Wnt/β-catenin signaling promotes aging-associated hair graying in mice
A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
research Morphological analysis of in vitro human hair growth
Human hair follicles can grow and stay healthy for up to 8 days in a lab setting.
research mTORC1 activity negatively regulates human hair follicle growth and pigmentation
High mTORC1 activity slows hair growth and causes it to lose color.
research Expression of NAD+dependent 15-hydroxyprostaglandin dehydrogenase and protection of prostaglandins in human hair follicle
A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.
research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth
Low ERCC3 gene activity is linked to non-pigmented hair growth.
research Sox2 in the dermal papilla regulates hair follicle pigmentation
Sox2 controls hair color by affecting pigment production in hair follicles.
research Dermal papilla cells and melanocytes response to physiological oxygen levels depends on their interactions
Low oxygen levels improve the function of hair and skin cells when they are in direct contact.
research Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro
Gambogic Amide helps maintain hair color and promotes hair growth.
research Exposure to gamma-rays at the telogen phase of the hair cycle inhibits hair follicle regeneration at the anagen phase in mice
Gamma-rays exposure during the resting phase of hair growth can damage hair regeneration and color in mice.
research Lipid‐mediated signalling and melanocyte function
A sphingolipid from human placenta may help treat vitiligo by activating melanocyte stem cells.
research Hair Graying Regulators Beyond Hair Follicle
Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
research The effects of gamma rays on the regeneration of hair follicles are carried over to later hair cycles
Gamma-ray exposure can cause long-lasting damage to hair follicles, affecting hair structure and color.
research Stem Cells of the Hair Follicular Tissue: Application in Cell Based Therapy for Vitiligo
Hair follicle stem cells could be used to treat the skin condition vitiligo.
research Biology of melanocytes in mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research An exclusive review of melatonin effects on mammalian melanocytes and melanoma
Melatonin may inhibit melanoma growth and has potential as a cancer therapy aid, but its effects on human skin pigmentation need more research.
research Dermal papilla regulation of hair growth and pigmentation
Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
research Cutaneous malignant melanoma incidences analyzed worldwide by skin type over advancing age of males and females: Evidence estrogen and androgenic hair are risk factors
Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.
research ERK1/2 Pathway Is Involved in the Enhancement of Fatty Acids from Phaeodactylum tricornutum Extract (PTE) on Hair Follicle Cell Proliferation
Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.
research Premature Greying of Hair (Premature Canities): A Concern for Parent and Child
Genetics, stress, and health issues can cause early hair greying, which affects self-esteem, and there's no cure, only hair dye.
research Micro-Injury Induces Hair Regeneration and Vitiligo Repigmentation Through Wnt/ β-Catenin Pathway
Micro-injury can help regrow hair and repigment vitiligo by activating specific cells.