44 citations
,
June 2018 in “Journal of Cellular Physiology” Researchers developed a 3D model of human hair follicle cells that can help understand hair growth and test new hair loss treatments.
44 citations
,
January 2011 in “Journal of biotechnology” Scientists recreated human hair follicles in the lab that can grow hair.
43 citations
,
August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
42 citations
,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Hair growth is influenced by various body and external factors, and neighboring hairs communicate to synchronize regeneration.
41 citations
,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
38 citations
,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
38 citations
,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
31 citations
,
August 2019 in “Regenerative Medicine” Human placenta hydrogel helps restore cells needed for hair growth.
31 citations
,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
30 citations
,
April 2017 in “Experimental Dermatology” Hair follicle stem cells and skin cells show promise for hair and skin therapies but need more research for clinical use.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.
29 citations
,
January 2017 in “Journal of Investigative Dermatology” The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.
28 citations
,
February 2016 in “F1000Research” Understanding glycans and enzymes that alter them is key to controlling hair growth.
27 citations
,
March 2018 in “Biomaterials” Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
26 citations
,
August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
26 citations
,
October 2012 in “Dermatologic Clinics” The document details hair transplantation techniques and innovations, highlighting Follicular Unit Transplantation as the standard and discussing the effectiveness and challenges of the procedure.
25 citations
,
July 2008 in “British Journal of Dermatology” CD10 and CD34 levels change during hair development and different hair growth stages, which could be important for hair regeneration treatments.
25 citations
,
May 1994 in “Journal of Investigative Dermatology” Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.
24 citations
,
November 2003 in “The FASEB Journal” Epimorphin helps start hair growth in mice.
24 citations
,
September 2019 in “Experimental cell research” BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
24 citations
,
January 2019 in “Science China Life Sciences” Chitosan/LiCl composite scaffolds help heal deep skin wounds better.
23 citations
,
January 2021 in “Scientific Reports” Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
23 citations
,
June 2016 in “FEBS Journal” Boosting β-catenin signaling in certain skin cells can enhance hair growth.
23 citations
,
December 2001 in “Lasers in Surgery and Medicine” Permanent hair removal is hard, but using longer laser pulses at lower power might improve results.
22 citations
,
October 2018 in “Aesthetic Plastic Surgery” Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.
22 citations
,
May 2011 in “Molecular Biology of the Cell” Integrin-linked kinase is crucial for normal skin healing.
21 citations
,
October 2013 in “Molecular Biology of the Cell” The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
18 citations
,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
18 citations
,
August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
17 citations
,
December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.