33 citations
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December 1982 in “Developmental Medicine & Child Neurology” Hair-shaft abnormalities can indicate neurological disorders, some of which are treatable.
31 citations
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December 2002 in “Biochimica et biophysica acta. G, General subjects/Biochimica et biophysica acta. General subjects (Online)” The research found two types of calcium in human hair, one that varies among individuals and another that is consistent across people.
30 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” TGase 3 helps build hair structure by forming strong bonds between proteins.
29 citations
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August 2011 in “PubMed” Hair and nail proteins, mainly keratins, are crucial for structure and can indicate health issues.
23 citations
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October 2021 in “Cell Stem Cell” Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
23 citations
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February 2015 in “The American journal of pathology” Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.
23 citations
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July 1989 in “Postgraduate medical journal” Spironolactone did not make hair thinner in women with excess hair growth.
22 citations
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January 2010 in “Clinical Medicine Insights Endocrinology and Diabetes” Forearm hair has more cortisol than lower leg hair.
22 citations
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January 2020 in “PeerJ” Keratin peptides in hair might help identify gender and ethnicity.
19 citations
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March 1988 in “International Journal of Dermatology” Hair shaft dysplasias are abnormal hair conditions that can be inherited or acquired and may signal other health issues, with limited treatment options available.
17 citations
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February 2013 in “PLOS ONE” 6-Gingerol, found in ginger, may slow down hair growth and could be used for hair removal.
16 citations
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October 2012 in “British Journal of Dermatology” Chemotherapy can cause significant hair thinning and changes in hair texture, while tamoxifen has a smaller effect.
15 citations
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June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
15 citations
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March 1996 in “PubMed” Anorexia nervosa may cause a hair defect called pili torti due to malnutrition and high vitamin A levels.
14 citations
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June 2005 in “PubMed” A rare ear cyst contained hair fragments.
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April 2019 in “iScience” EGFR helps control how hair grows and forms without needing p53 protein.
13 citations
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March 2019 in “PLoS ONE” A new method improves protein analysis in hair, aiding health and disease research.
12 citations
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October 1996 in “Dermatologic clinics” Advances in genetics may lead to targeted treatments for hair disorders.
11 citations
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May 2013 in “Journal of Investigative Dermatology” KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
10 citations
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January 2011 in “Journal of biomedical optics” OCT is a reliable, noninvasive way to measure hair thickness.
10 citations
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January 2004 in “Dermatologic Surgery” Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.
8 citations
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February 2016 in “The American Journal of Dermatopathology” Hair transplants can make hair follicles larger and hair shafts thicker.
8 citations
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July 2013 in “PLoS ONE” DNA can be quickly and effectively extracted from hair using laundry powder.
7 citations
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December 2014 in “Journal of dermatology” Hair shaft miR-221 levels can help detect malignant melanoma.
7 citations
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March 2003 in “Journal de Physique IV (Proceedings)” Calcium soaps are present in human hair and can be removed with acid.
7 citations
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March 2020 in “Journal of the American Academy of Dermatology” EGFR inhibitors often cause dry, brittle hair and eyebrow/eyelash changes.
7 citations
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September 2017 in “Scientific Reports” Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
7 citations
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December 2015 in “PloS one” Cryopreserved mouse whisker follicles can grow hair when transplanted into nude mice.
7 citations
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March 2004 in “Journal of the American Academy of Dermatology” Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.
6 citations
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January 2016 in “Annals of Dermatology” Human hair contains more glycosaminoglycans in children than adults, and these compounds decrease with age, possibly affecting hair thickness.