236 citations
,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
193 citations
,
January 2015 in “International journal of trichology” Dermatologists need to understand hair products to treat hair and scalp issues better.
80 citations
,
June 2008 in “Biomaterials” EVAL membranes help create cell structures that can regrow hair follicles.
70 citations
,
February 2017 in “Dermatologic Surgery” Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
31 citations
,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
29 citations
,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
28 citations
,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
27 citations
,
February 2017 in “Clinical, Cosmetic and Investigational Dermatology” New compounds were found to help increase hair growth and decrease hair loss.
23 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
21 citations
,
November 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Telogen is an active phase with important biological processes, not a resting phase.
18 citations
,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
17 citations
,
October 2015 in “Medicine and Pharmacy Reports” Animal models are crucial for learning about hair loss and finding treatments.
11 citations
,
March 2013 in “Journal of Applied Biomedicine” β-catenin helps hair follicle stem cells grow by activating a specific cell pathway.
11 citations
,
January 2001 in “Cambridge University Press eBooks” Androgens can cause hair growth in some areas but hair loss on the scalp.
10 citations
,
May 2020 in “Dermatology Research and Practice” Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
2 citations
,
May 2017 in “InTech eBooks” Stem cells could improve hair growth and new treatments for baldness are being researched.
1 citations
,
November 2011 in “Dermatologica Sinica” Women using hair relaxers with alopecia had lower zinc levels, suggesting zinc deficiency might contribute to hair loss.
1 citations
,
July 2005 in “Drugs and the pharmaceutical sciences” Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.
January 2025 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” Oral minoxidil boosts hair growth and reduces shedding in androgenetic alopecia.
December 2023 in “International Journal For Multidisciplinary Research” Indian medicinal plants can help with hair growth and common hair issues.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
January 2022 in “Clinical dermatology open access journal” Certain cannabinoids may help increase hair growth and could be useful for treating hair loss.
September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
June 2012 in “Springer eBooks” Eating disorders can cause various hair problems, and while hair loss in these disorders is linked to metabolic syndrome, treatment focuses on specific medications and lifestyle changes for the syndrome.
January 2012 in “Postgraduate obstetrics & gynecology” Up to 50% of women may experience significant hair loss by age 50, with various causes and treatments available.
January 2012 in “Postgraduate obstetrics & gynecology” Up to half of women by age 50 experience significant hair loss, with various types and treatments available.
44 citations
,
February 2012 in “The journal of neuroscience/The Journal of neuroscience” Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.
25 citations
,
March 2017 in “Experimental Dermatology” The document concludes that understanding hair follicles requires more research using computational methods and an integrative approach, considering the current limitations in hair treatment products.
224 citations
,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
63 citations
,
March 2000 in “Annals of clinical psychiatry” Some psychiatric medications can cause hair loss, but it usually grows back after adjusting the medication.