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August 1990 in “PubMed” Keratins K1 and K10 are found in the inner root sheath and cuticle of human hair follicles.
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September 1996 in “Differentiation” The upper dermal sheath can regenerate hair in rats.
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December 1991 in “Annals of the New York Academy of Sciences” ORS and hair matrix cells balance growth and differentiation better than normal keratinocytes, with human dermal fibroblasts crucial for proper differentiation.
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February 2004 in “British Journal of Dermatology” Keratin in mouse hair follicles is complex and plays specific roles.
22 citations
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March 2017 in “Scientific reports” Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.
22 citations
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June 2008 in “Experimental Dermatology” Heparanase is essential for hair follicle health and inner root sheath differentiation.
19 citations
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September 2019 in “British Journal of Dermatology” FOL-005 peptide can reduce human hair growth by lowering FGF7 levels.
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September 2009 in “European Journal of Histochemistry” CD90 is abundantly present on stem-like cells in dog hair follicles.
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January 2002 in “Biochemical and biophysical research communications” Interferon β from hair cells stops the growth of other hair cells.
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Sex hormones and antiandrogens can either stimulate or inhibit human hair follicle cell growth depending on the dose.
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December 2018 in “The American Journal of Dermatopathology” Early shedding of the inner root sheath in noninflamed hair follicles is a relatively specific sign of Central Centrifugal Cicatricial Alopecia.
6 citations
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December 1990 in “PubMed” Keratinocytes in hair follicles differentiate similarly to skin cells, with specific patterns in different regions.
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August 2012 in “Journal of Dermatology” Tamoxifen may cause female hair loss by increasing androgen receptor expression.
4 citations
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April 1989 in “The Journal of Dermatology” Trichohyalin granules help inner root sheath cells in hair follicles harden by integrating with keratin filaments.
3 citations
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November 2019 in “Journal of Investigative Dermatology” Adenosine helps human hair grow and prevents hair loss by targeting specific cells.
March 2026 in “Journal of Bioscience and Bioengineering” Oxytocin from hair cells helps hair growth and stem cell increase.
February 2026 in “Nature Communications” Inhibiting connective tissue sheath contraction may improve hair growth in male pattern baldness.
July 2024 in “Biological and Pharmaceutical Bulletin” Licorice extract helps hair growth and may treat hair loss.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Abnormal contraction of connective tissue in hair follicles causes hair loss by killing off important cells, and treating this could improve hair growth.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” JAK inhibitors help hair growth by boosting beta-catenin activity in hair root cells.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
May 2022 in “Research Square (Research Square)” Nestin marks cells that can become a specific type of skin cell in hair follicles of both developing and adult mice.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific mutation in the TRPV3 gene causes hair follicle cells to develop improperly, leading to hair loss.
September 2018 in “Cosmetics” Inositol and arginine solutions improve hair follicle health and turnover.
November 2016 in “Oncology Letters” Milia may come from the outer part of the hair follicle.
January 2000 in “Acta Academiae Medicine Militaris Tertiae” Epidermal growth factor boosts growth of hair follicle cells.
Culturing hair follicles at the air-liquid interface with minoxidil significantly boosts hair growth and preserves the root sheath.
March 2020 in “Central European Journal of Biology” The study found that stem cells and neutrophils are important for regenerating hair follicle structures in mice.
11 citations
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April 1982 in “Journal of the Forensic Science Society” Enzyme presence in hair sheath cells decreases over time, affecting forensic analysis.
52 citations
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May 2015 in “Cytotherapy” DS-MSCs from hair follicles may improve diabetic wound healing.