December 2025 in “Neurobiology of Stress” People who recently attempted suicide during depression showed signs of adrenal fatigue, but had higher DHEA levels around the attempt time.
38 citations
,
September 2013 in “Therapeutic Drug Monitoring” First Nation individuals had higher hair cortisol levels, indicating more chronic stress.
30 citations
,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
13 citations
,
January 2016 in “Annals of Dermatology” Stress can slow hair growth by affecting certain cells and pathways.
5 citations
,
October 2021 in “Signal Transduction and Targeted Therapy” Stress hormone corticosterone suppresses hair growth by affecting stem cell activity and Gas6 protein expression.
4 citations
,
June 2025 in “JMIR Formative Research” Hair cortisol concentration may reflect some physiological stress but doesn't strongly correlate with perceived stress.
4 citations
,
February 2022 in “Frontiers in molecular biosciences” Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
3 citations
,
January 2022 in “Neurotoxicity Research” Botulinum toxin may help reduce stress-related hair loss.
November 2025 in “Journal of Laboratory Medicine” Chronic stress increased after lockdown, especially in young adults and females.
August 2025 in “Journal of the Korean Society of Cosmetology” Hair loss stress increases interest in appearance and buying scalp care products.
April 2024 in “Advances in Redox Research” Human hair strength and health are linked to sulfur compounds that can be reduced by stress but improved with sulfur supplements.
The mutation helps mice handle heat better without affecting hair growth.
March 2018 in “Digital Access to Scholarship at Harvard (DASH) (Harvard University)” Chronic stress delays hair growth and affects hair stem cells negatively.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
210 citations
,
May 2006 in “The FASEB journal” Oxidative stress causes hair to gray by damaging and killing pigment cells.
127 citations
,
December 2005 in “Experimental Dermatology” Stress can stop hair growth in mice, and treatments can reverse this effect.
126 citations
,
January 2009 in “International Journal of Trichology” Oxidative stress contributes to hair graying and loss as we age.
69 citations
,
August 2016 in “PubMed” High stress can disrupt hair growth, but certain supplements might help.
67 citations
,
August 2013 in “International Journal of Cosmetic Science” Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
58 citations
,
October 2016 in “Journal of Investigative Dermatology” Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
41 citations
,
June 2024 in “Journal of Cellular and Molecular Medicine” Natural antioxidants may help prevent hair loss by reducing oxidative stress.
40 citations
,
January 2018 in “International journal of trichology” Healthy scalp reduces hair loss by managing oxidative stress.
33 citations
,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
22 citations
,
July 2015 in “PloS one” Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
14 citations
,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
10 citations
,
December 2018 in “Journal of animal physiology and animal nutrition” Heat stress reduced hair growth and affected related genes in rex rabbits.
8 citations
,
July 2010 in “Aesthetic Plastic Surgery” Adding more glutathione to the preservation solution doesn't reduce oxidative stress in hair transplants.
6 citations
,
July 2022 in “The FASEB Journal” Methionine helps improve hair growth in heat-stressed rabbits.
6 citations
,
May 2022 in “Frontiers in Medicine” The study suggests pandemic stress might worsen or trigger hair loss problems.
6 citations
,
December 2019 in “BMC Complementary and Alternative Medicine” Alcohol extract from Vernonia anthelmintica seeds may help treat stress-related hair loss.