318 citations
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January 2022 in “Signal Transduction and Targeted Therapy” The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
182 citations
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November 2018 in “Cosmetics” Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.
153 citations
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April 1998 in “Current Biology” The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
136 citations
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April 2010 in “British Journal of Dermatology” Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.
85 citations
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March 2008 in “Journal of Cell Science” The mutation causing Hutchinson-Gilford progeria syndrome leads to severe skin problems and early death in mice.
67 citations
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September 2017 in “Cell Reports” Caloric restriction improves skin and fur structure but can cause muscle loss and movement issues.
51 citations
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August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
39 citations
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April 1992 in “Development” Both cell and non-cell parts are important for rat whisker follicle regrowth.
37 citations
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May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
30 citations
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November 2024 in “ACS Materials Au” Microneedles are promising for disease monitoring and drug delivery due to their minimal invasiveness and versatility.
30 citations
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January 2023 in “EFSA journal” Adults should not consume more than 255 micrograms of selenium per day to avoid risk of hair loss and other side effects.
26 citations
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August 2008 in “Clinical endocrinology” The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.
22 citations
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June 2017 in “Stem cell reports” PTEN helps control the number and health of skin stem cells by working with the protein BMAL1.
21 citations
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August 2017 in “Journal of veterinary internal medicine” Combining amino acid and stem cell therapy may help manage hepatocutaneous syndrome in dogs.
19 citations
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October 2024 in “Molecular Pharmaceutics” Microneedles improve delivery of plant-based compounds through the skin, aiding treatments for hair loss, cancer, and wounds.
18 citations
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December 2021 in “Foods” Seaweeds contain beneficial compounds with potential uses in food, cosmetics, and health, but more research is needed to improve extraction and safety.
15 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
15 citations
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July 2015 in “Developmental Dynamics” Orai1 protein is crucial for tooth development and affects enamel thickness and mineralization.
12 citations
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January 2021 in “Journal of Cutaneous and Aesthetic Surgery” Epidermal growth factor helps skin and hair regeneration but needs more research for better understanding.
10 citations
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August 2024 in “ACS Omega” Nanocosmetics with natural extracts offer benefits but need more research on safety and environmental impact.
9 citations
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May 2023 in “Stem Cell Research & Therapy” Stem cell treatment from umbilical cords reduces symptoms of atopic dermatitis and may help hair growth.
9 citations
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November 2022 in “Applied sciences” Marine algae compounds may improve skin health and promote hair growth.
2 citations
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September 2025 in “International Journal of Nanomedicine” Extracellular vesicles can help treat skin issues like wounds, hair loss, aging, and inflammation.
2 citations
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August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
2 citations
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September 2022 in “Cytotherapy” Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.
1 citations
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January 2023 in “International journal of molecular sciences” Rabbits with Sarcoptes scabiei had thicker skin, cell death, and skin hardening.
Kombucha tea extract may protect skin from damage in hot and humid conditions.
The new biomimetic skin heals wounds faster and better than traditional treatments, without scarring.
October 2025 in “Gene Expression” Exosome therapy could be a promising new way to treat hair loss.
October 2025 in “Bioactive Materials” Combining traditional Chinese medicine with microneedles shows promise for effectively treating skin diseases with fewer side effects.