research Tfap2b specifies an embryonic melanocyte stem cell that retains adult multi-fate potential
The gene Tfap2b is essential for creating a type of stem cell in zebrafish that can become different pigment cells.
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research Hair Sciences: The hair cycle discussed with Dr. Gilliam Westgate
Androgens affect hair growth and shedding, with genetic and non-genetic factors influencing baldness.
research Dissecting Cellulitis of the Scalp
Dissecting cellulitis of the scalp is a condition that causes inflammation and scarring on the scalp, mainly affecting African-American men, and can lead to permanent hair loss.
research Alopecia: possible causes and treatments, particularly in captive nonhuman primates.
Alopecia in captive primates can be caused by many factors, so thorough testing is needed before blaming stress.
research Animal and in vitro Models for the Study of Hair Follicles
Understanding hair follicles through various models can help develop new treatments for hair disorders.
research The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment
Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.
research Third International Research Workshop on Alopecia Areata
Alopecia areata is complex, with genetic and immune factors, and animal models are key for future treatment research.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle
A specific genetic change in the KRT71 gene causes a hair loss condition in Hereford cattle.
research Wound repair at a glance
Wound healing is a complex, multi-phase process involving various cells and activities to repair skin damage.
research Keratins of the Human Hair Follicle
More research is needed to understand how hair keratins work and their role in hair disorders.
research Endocrine Influences on Hair Growth
Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.
research Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Fullerene C60 with cytoprotective and cytotoxic potential: prospects as a novel treatment agent in Dermatology?
Fullerene C60 shows promise as a new treatment for various skin conditions.
research Gsdma3 is required for hair follicle differentiation in mice
The Gsdma3 gene is essential for normal hair development in mice.
research Milestones in Photocarcinogenesis
UV radiation causes skin cancer, but sunscreens and certain drugs can help prevent it.
research Wound Regeneration Deficit in Rats Correlates with Low Morphogenetic Potential and Distinct Transcriptome Profile of Epidermis
Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
research p53 Is a Direct Transcriptional Repressor of Keratin 17: Lessons from a Rat Model of Radiation Dermatitis
The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.
research Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis
Activating Notch signaling can kill basal cell carcinoma cells.
research Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature
Plucked hair follicles can help diagnose scalp lupus.
research Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches
New treatments like nanotechnology show promise in improving skin cancer therapy.
research A Two-Stepped Culture Method for Efficient Production of Trichogenic Keratinocytes
A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
research CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen
Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
research The Roles of Non-coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives
Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
research Longitudinal Assessment of the Prevalence of Actinic Keratosis and Extensive Risk Factor Evaluation: An Update from the Rotterdam Study
Actinic keratosis is more common in older men with certain genetic traits, but smoking seems to reduce its odds.
research Frontal fibrosing alopecia: a disease that remains enigmatic
Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.
research Construction of transcriptome atlas of white yak hair follicle during anagen and catagen using single-cell RNA sequencing
The research improved understanding of yak hair growth to help use yak wool better.
research Clinically relevant aberrant Filip1l DNA methylation detected in a murine model of cutaneous squamous cell carcinoma
Increased methylation of the Filip1l gene may contribute to aggressive skin cancer.
research Spatiotemporal Labeling of Melanocytes in Mice
The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
research Alopecia types, current and future treatment
Current alopecia treatments manage symptoms but don't cure, and better treatments are needed.