April 1974 in “Pediatric Research” The Naked (N) trait in mice is linked to lower glycine and tyrosine in hair proteins.
April 2022 in “Medical Molecular Morphology” 25 citations
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November 2020 in “Proceedings of the National Academy of Sciences” HoxC genes are crucial for normal hair and nail development.
7 citations
,
February 1962 in “Experimental Biology and Medicine” Male and female mice have different lipid compositions in their skin during hair growth cycles.
115 citations
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December 2001 in “Endocrinology” Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.
10 citations
,
January 2004 in “Journal of Investigative Dermatology” Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.
5 citations
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August 2015 in “Bioscience, Biotechnology, and Biochemistry” Obese mice with a leptin gene mutation have a longer resting phase in their hair cycle, which may help understand certain hair loss conditions.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Both induced and spontaneous AA lymphocytes can cause alopecia areata in mice.
46 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
8 citations
,
January 2015 in “Clinical and Experimental Dermatology” A new model for hair regeneration in mice was created in 2015, which is faster and less invasive than the old method, producing normal hairs in about 21 days.
33 citations
,
July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
32 citations
,
May 1999 in “Biochemical and Biophysical Research Communications” A new enzyme, BSSP, is found in high amounts in the hair follicles of nude mice.
67 citations
,
April 2014 in “Biochemical Journal” Ceramide synthase 4 deficiency in mice leads to hair loss due to altered sebum lipids.
72 citations
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November 2002 in “Journal of Investigative Dermatology” Estrogen receptor α controls hair growth cycles and skin thickness in male mice.
1 citations
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January 1972 in “PubMed”
September 2023 in “Cells tissues organs” Mice skin matures by day 200, leading to aging signs like curved hair follicles and white hairs due to changes in skin stem cells.
50 citations
,
February 2004 in “Genomics” A gene mutation causes lanceolate hair in rats by disrupting hair shaft integrity.
14 citations
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September 1999 in “Mammalian genome” The scraggly mutation causes hair loss and skin defects in mice.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
January 2008 in “한국미용학회지” Certain enzymes and a growth factor were higher in mice treated with minoxidil or a peppermint and rosemary oil mix, which may be good indicators of hair growth.
76 citations
,
March 2005 in “Journal of Molecular Medicine” Certain mice without specific receptors or mast cells don't lose hair from stress.
November 2013 in “Institutional Repositories DataBase (IRDB)” Gamma-ray exposure during hair rest phase harms hair growth and color in mice.
April 2018 in “Journal of Investigative Dermatology” Mutations in Far2 mice cause hair loss due to sebaceous gland issues.
81 citations
,
September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
6 citations
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August 2001 in “PubMed” The stump-tailed macaque is a good model for studying human hair loss, but it's expensive and hard to find, while rodent models are promising for understanding hair growth and finding new treatments.
August 2001 in “The Journal of Cell Biology” A new keratin gene was found in mice, explaining hair growth.
1 citations
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April 2024 in “Journal of Pharmaceutical and Pharmacological Sciences” The mouse models are effective for testing new hair loss treatments.
March 2025 in “ACS Applied Materials & Interfaces” Ultrasonic microneedles improve hair regrowth treatment effectiveness without side effects.
21 citations
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December 2001 in “Endocrinology” Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.
April 2014 in “The FASEB Journal” Iron deficiency in mothers causes hair loss in their baby mice.