81 citations
,
January 2006 in “Journal of cellular physiology” Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.
78 citations
,
November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
66 citations
,
December 1999 in “Journal of Investigative Dermatology” New mutations in the hairless gene may cause hair loss and affect bone development.
52 citations
,
October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
28 citations
,
July 2002 in “Dermatologic Surgery” Understanding scalp anatomy is crucial for successful and safe scalp surgery.
27 citations
,
June 2020 in “Genes” Lykoi cats' unique sparse hair is linked to specific genetic variants in the Hairless gene.
26 citations
,
December 2011 in “Journal of Investigative Dermatology” New gene identification techniques have improved the understanding and classification of inherited hair disorders.
24 citations
,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
15 citations
,
December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
14 citations
,
June 2021 in “British journal of dermatology/British journal of dermatology, Supplement” Experts agreed on guidelines to improve research on Frontal Fibrosing Alopecia.
11 citations
,
May 2019 in “BioMed Research International” Hair transplantation effectively treats scalp scars with high success and patient satisfaction.
11 citations
,
May 2009 in “Medical Hypotheses” Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
11 citations
,
December 1921 in “Archives of dermatology and syphilology” A rare scalp disease causes hair loss, pus-filled nodules, and scarring.
10 citations
,
March 2019 in “Human Genetics” A genetic mutation in the SGK3 gene causes hairlessness in Scottish Deerhounds and may relate to human hair loss.
10 citations
,
January 2018 in “Elsevier eBooks” Burn scars heal abnormally and more research is needed to find better treatments.
10 citations
,
August 2013 in “Experimental Dermatology” Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.
8 citations
,
January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” A specific thyroid hormone resistance mutation may be linked to different types of hair loss.
8 citations
,
April 2016 in “Experimental dermatology” B6.Cg-Tyr c−2J Hr hr /J mice have a stronger delayed sunburn reaction and are good for UV research.
7 citations
,
November 2000 in “Clinics in Dermatology” Most hair loss in children is caused by a few common conditions and is easy to diagnose, but rare types require careful evaluation.
6 citations
,
November 2021 in “Oncology Research and Treatment” Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.
6 citations
,
March 2017 in “Plastic and reconstructive surgery. Global open” Both pretrimmed and direct nonshaven methods are effective for hair transplants; pretrimmed takes longer but yields denser, longer hair.
5 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease” Hairless protein helps control hair growth by regulating vitamin D receptor activity.
4 citations
,
August 2020 in “Facial plastic surgery & aesthetic medicine” Combining growth factors with minoxidil improves hair growth more than minoxidil alone.
1 citations
,
January 2021 in “Skin appendage disorders” Chemotherapy patients don't all lose their hair due to factors like hair growth rates, age, genetics, and the type of drugs used.
1 citations
,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
September 2022 in “Institutional Repositories DataBase (IRDB)” 3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.
Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.
Researchers developed a cost-effective, ethical skin model using hairless guinea pig cells for toxicology studies.
14 citations
,
January 2016 in “Elsevier eBooks” Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.
434 citations
,
October 2003 in “PTR. Phytotherapy research/Phytotherapy research” Natural products in cosmetics are beneficial for skin and hair care with low toxicity.