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research Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss

19 citations , July 2020 in “EBioMedicine”

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

research 4‐octyl itaconate alleviates cisplatin‐induced ferroptosis possibly via activating the NRF2/HO‐1 signalling pathway

1 citations , March 2024 in “Journal of Cellular and Molecular Medicine”

4-octyl itaconate may prevent hearing loss caused by the drug cisplatin by activating certain cell protection pathways.

research Pili Trianguli et Canaliculi Is a Defect of Inner Root Sheath Keratinization

8 citations , May 2005 in “The American journal of dermatopathology/American journal of dermatopathology”

The hair defect is due to abnormal inner root sheath keratinization.

research HUMAN HAIR KERATIN PROTEIN, HAIR FIBERS AND HYDROXYAPATITE (HA) COMPOSITE SCAFFOLD FOR BONE TISSUE REGENERATION

January 2014

research De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks

2 citations , February 2021 in “FEBS open bio”

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

research A pair of transmembrane receptors essential for the retention and pigmentation of hair

11 citations , May 2012 in “Genesis”

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

research Gpr54 deletion accelerates hair cycle and hair regeneration

1 citations , November 2024 in “EMBO Reports”

Deleting Gpr54 speeds up hair growth and regeneration.

research Ultrahigh-Power Sonicator Lysis Enables Deep ProteomicProfiling of Hair Shafts for Fetal Growth Restriction Biomarker Discovery

November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

A new method helps find proteins in hair to identify fetal growth issues.

research SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation

April 2026 in “Cellular and Molecular Immunology”

SPT6 prevents excessive skin inflammation by blocking a feedback loop.

research Molecular mechanism for transcriptional regulation of the parathyroid hormone gene by Epiprofin

March 2025 in “FEBS Journal”

Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.

research Butyrophilin-like 2 (BTNL2) to the Rescue: controlling autoaggressive dermal gamma delta (GD) T lymphocytes in human hair follicles (HFs) 3747

November 2025 in “The Journal of Immunology”

BTNL2 helps protect hair follicles from immune attacks, which could aid in treating alopecia areata.

research Dehydroepiandrosterone- and glucose-6-phosphate-dehydrogenases in the hair cycle of the rat

7 citations , January 1971 in “Archives of Dermatological Research”

research Author response: Generation of inner ear hair cells by direct lineage conversion of primary somatic cells

1 citations , May 2020

Four transcription factors can convert mouse cells into hair cell-like cells, aiding hearing loss research and treatment.

research The Shaven (Sha) Mutation, Chromosome 15

1 citations , August 2020

The Shaven mutation in mice affects hair growth and causes a greasy coat due to abnormal lipid content.

research Faculty Opinions recommendation of Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture.

May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

A mutation in the KRT74 gene causes woolly hair by affecting hair texture.

research (The)Hair growth promoting effect of HEM-13HDC (a mixture of 8 herbal extracts) and its molecular regulation

January 2004

HEM-13HDC, a mix of 8 herbal extracts, helps hair grow and affects hair growth at a molecular level.

research Dermal papilla-induced hair differentiation of adult epithelial stem cells from human skin

90 citations , August 2004 in “Physiological Genomics”

Dermal papilla cells help skin stem cells grow into hair.

research 3P343 Change of cell membrane complex of a hair fiber caused by hair damage

January 2005 in “Seibutsu Butsuri/Seibutsu butsuri”

Chemical treatments damage hair more than UV exposure, making it thinner and less flexible.

research LB1777 A novel ex vivo model of human hair follicle immune privilege collapse reveals the potential of farudodstat, a DHODH inhibitor, as a therapeutic for alopecia areata treatment

1 citations , August 2023 in “Journal of Investigative Dermatology”

Farudodstat may help treat alopecia areata by protecting hair follicles.

research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene

January 2024 in “Animals”

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

research Sequence and expression of human hair keratin genes

19 citations , July 1994 in “Journal of Dermatological Science”

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

research Use of primary keratinocyte cultures from plucked human hairs for analysis of gap junctional intercellular communication

3 citations , January 1991 in “Toxicology in Vitro”

Hair follicle cultures are effective for studying cell communication and testing chemicals.

research Faculty Opinions recommendation of Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture.

May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

A mutation in the KRT74 gene causes woolly hair by affecting hair texture.

research 244 Defective maintenance of hair follicle stem cells through COL17A1 loss orchestrates the hair follicle aging program

September 2017 in “Journal of Investigative Dermatology”

Loss of COL17A1 causes hair follicle stem cells to age and leads to hair loss.

research Identification of a Novel MPL Loss of Function Mutation in a Patient with Cyclic Thrombocytopenia and Characterization of This Syndrome

4 citations , December 2016 in “Blood”

A new gene mutation may cause cyclic thrombocytopenia by affecting platelet production.

Analysis of lncRNAs Expression Profiles in Hair Follicles of Hu Sheep Lambskin

research Analysis of lncRNAs Expression Profiles in Hair Follicle of Hu Sheep Lambskin

17 citations , June 2020 in “Animals”

lncRNAs may regulate hair follicle development in Hu sheep.

research Comparison of Polynucleotide and Polydeoxyribonucleotide in Dermatology: Molecular Mechanisms and Clinical Perspectives

2 citations , August 2025 in “Pharmaceutics”

PN hydrates skin; PDRN heals and regenerates skin and hair.

research Hyaluronic Acid Microneedles Loaded with ChineseHerbalExtracts as an Intradermal Delivery System for Hair Regeneration

April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Hyaluronic acid microneedles with herbal extracts may effectively promote hair growth for treating hair loss.

research Cloning and Activity of Mouse Ultra-High Sulfur Keratin Gene Promoter

January 2010 in “Acta Laboratorium Animalis Scientia Sinica”

The UHS promoter is specific to mouse hair follicles.

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