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research Three-dimensional modelling of interchain sequence similarities and differences in the coiled-coil segments of keratin intermediate filament heterodimers highlight features important in assembly

13 citations , November 2007 in “Journal of Structural Biology”

Keratin heterodimers are preferred for their specific and structural advantages.

research Observation of different HHK groups with SEM

January 2000 in “Zhongguo yixue wulixue zazhi”

Different human hair keratin types have unique structures that affect how they dissolve and can be used to create self-tendons.

research Relative Amounts of Keratin 17 Are Higher Than Those of Keratin 16 in Hair-Follicle-Derived Tumors in Comparison with Nonfollicular Epithelial Skin Tumors

31 citations , March 1995 in “Journal of Investigative Dermatology”

research Histochemical observations of lectin-binding sites and keratin distribution in calcifying epithelioma of Malherbe.

6 citations , January 1985 in “ACTA HISTOCHEMICA ET CYTOCHEMICA”

Tumor cells in calcifying epithelioma of Malherbe resemble hair follicle cells.

research Functional analysis of keratin components in the mouse hair follicle inner root sheath

23 citations , February 2004 in “British Journal of Dermatology”

Keratin in mouse hair follicles is complex and plays specific roles.

research The interaction between surfactants and keratinous tissues

39 citations , January 1979 in “Journal of the Society of Cosmetic Scientists of Korea”

Surfactants can protect or harm hair, skin, and nails, depending on their type and use.

research The structure of human trichohyalin : potential multiple roles as a functional ef-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein

2 citations , January 1993

Trichohyalin is a versatile protein involved in hair and skin structure.

research [Immunohistochemical study on the keratin expression in generating rat hair tissues using anti-hair keratin monoclonal antibodies].

July 1990 in “PubMed”

Hair germ cells differ from epidermal cells in keratin expression, and specific keratins form after hair differentiation.

research Frequency of an electrophoretic variant of hair alpha keratin in human populations.

14 citations , January 1977 in “PubMed”

The hair keratin variant is mostly found in Caucasians.

research Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia

42 citations , October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mutations in the KRT85 gene cause hair and nail problems.

research Hair Follicle Keratins

1 citations , August 2020 in “CRC Press eBooks”

Hair growth can be influenced by manipulating keratin and growth factor genes.

research Crosslinking structure of keratin. V. Number and type of crosslinks in microstructures of untreated and potassium cyanide treated human hair

2 citations , September 1996 in “Journal of Applied Polymer Science”

Potassium cyanide changes hair's disulfide bonds to monosulfide, affecting high-sulfur proteins more.

research Specific repair of aging hair keratin

1 citations , October 2009 in “International Journal of Cosmetic Science”

A new keratin treatment can strengthen and protect aging hair.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

research Keratinization of outer root sheath cells is prevented by contact with inner root sheath of rat hair follicles

9 citations , July 2008 in “Archives of Dermatological Research”

research Properties of Partially Extracted Hairs and their Degradability by Proteases

January 2007 in “Sen'i Gakkaishi”

Mf-rich hair degrades more than Ma-rich hair, especially with Proteinase K.

research Keratinic amyloid deposition in canine hair follicle tumors

1 citations , October 2022 in “Veterinary pathology”

Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.

research Investigating the role of keratin proteins and microbial associations in hereditary and pathogenic alopecia

October 2024 in “Archives of Dermatological Research”

research Genomic Organization and Amplification of the Human Keratin 15 and Keratin 19 Genes

12 citations , January 2000 in “Biochemical and Biophysical Research Communications”

The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.

research Molecular elements of the regulatory control of keratin filament modulator AHF/trichohyalin in the hair follicle

7 citations , July 2008 in “Experimental Dermatology”

The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.

research Demethylation of methionine and keratin damage in human hair

11 citations , February 2018 in “Amino acids”

Copper and iron cause keratin damage in hair by converting methionine to homocysteine.

research The role of cathepsin E in terminal differentiation of keratinocytes

15 citations , April 2011 in “Biological Chemistry”

Cathepsin E is crucial for normal skin cell differentiation and development.

research Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins

63 citations , July 2006 in “British Journal of Dermatology”

Psoriasis causes changes in certain keratins and shrinks sebaceous glands in the scalp.

research Keratinization of sheath and calamus cells in developing and regenerating feathers

26 citations , August 2007 in “Annals of Anatomy - Anatomischer Anzeiger”

Feathers become harder as they develop due to a change in keratin type.

research Expression of Keratin 75 (K6hf) in Oral Squamous Cell Carcinoma

2 citations , January 2011 in “Dental Medicine Research”

Keratin 75 might be important in oral cancer progression.

research Immunohistochemical demonstration of keratins in the epidermal layers of the Malayan pangolin (Manis javanica), with remarks on the evolution of the integumental scale armour

28 citations , September 2013 in “European Journal of Histochemistry”

Keratins in Malayan pangolins vary by region, suggesting scales evolved from the tail towards the head.

research A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3

34 citations , January 2004 in “Genomics”

A cluster of 21 keratin-associated protein genes important for hair growth was found on human chromosome 21.

research Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair

119 citations , August 2008 in “BMC Evolutionary Biology”

KRTAP genes evolved early in mammals, leading to diverse hair traits.

research Proliferating trichilemmal cyst with histological malignant transformation: Identification of hair sheath keratins in the tumor.

3 citations , January 1989 in “The Nishinihon Journal of Dermatology”

A hair cyst can become cancerous, showing specific keratins from the hair sheath.

research Keratinocyte biology and pathology

33 citations , August 2014 in “Veterinary Dermatology”

Keratinocytes play a key role in skin health, but more research is needed.

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